Sallam, Karim

Almanac — Retrieval-Augmented Language Models for Clinical Medicine

Zakka, C., Shad, R., Chaurasia, A., Dalal, A. R., Kim, J. L., Moor, M., Fong, R., Phillips, C., Alexander, K., Ashley, E., et al. (2024) · NEJM AI

Artificial Intelligence in Healthcare and EducationMachine Learning in Healthcare

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Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy

Lee, J., Termglinchan, V., Diecke, S., Itzhaki, I., Lam, C. K., Garg, P., Lau, E., Greenhaw, M., Seeger, T., Wu, H., et al. (2019) · Nature

Cardiomyopathy and Myosin StudiesCardiac electrophysiology and arrhythmias

Cited by 222

Epigenetic regulation of phosphodiesterases 2A and 3A underlies compromised β-adrenergic signaling in an iPSC model of dilated cardiomyopathy

Wu, H., Lee, J., Vincent, L. G., Wang, Q., Gu, M., Lan, F., Churko, J. M., Sallam, K. I., Matsa, E., Sharma, A., et al. (2015) · Cell Stem Cell

Phosphodiesterase function and regulationPluripotent Stem Cells Research

Cited by 177

Human induced pluripotent stem cell–derived cardiomyocytes as an in vitro model for coxsackievirus B3–induced myocarditis and antiviral drug screening platform

Sharma, A., Marceau, C., Hamaguchi, R., Burridge, P. W., Rajarajan, K., Churko, J. M., Wu, H., Sallam, K. I., Matsa, E., Sturzu, A. C., et al. (2014) · Circulation Research

Viral Infections and Immunology ResearchPluripotent Stem Cells Research

Cited by 148

Clinical trial in a dish using iPSCs shows lovastatin improves endothelial dysfunction and cellular cross-talk in LMNA cardiomyopathy

Sayed, N., Liu, C., Ameen, M., Himmati, F., Zhang, J. Z., Khanamiri, S., Moonen, J.-R., Wnorowski, A., Cheng, L., Rhee, J.-W., et al. (2020) · Science Translational Medicine

Pluripotent Stem Cells ResearchCardiomyopathy and Myosin Studies

Cited by 111