Ishikawa, Toshihisa

Membrane transporters in drug development

The International Transporter Consortium, Giacomini, K. M., Huang, S.-M., Tweedie, D. J., Benet, L. Z., Brouwer, K. L. R., Chu, X., Dahlin, A., Evers, R., Fischer, V., et al. (2010) · Nature Reviews Drug Discovery

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

Cited by 3,340

Functional Validation of the Genetic Polymorphisms of Human ATP-Binding Cassette (ABC) Transporter ABCG2: Identification of Alleles That Are Defective in Porphyrin Transport

Tamura, A., Watanabe, M., Saito, H., Nakagawa, H., Kamachi, T., Okura, I., & Ishikawa, T. (2006) · Molecular Pharmacology

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

Cited by 141

A New Strategy of High-Speed Screening and Quantitative Structure-Activity Relationship Analysis to Evaluate Human ATP-Binding Cassette Transporter ABCG2-Drug Interactions

Saito, H., Hirano, H., Nakagawa, H., Fukami, T., Oosumi, K., Murakami, K., Kimura, H., Kouchi, T., Konomi, M., Tao, E., et al. (2006) · The Journal of Pharmacology and Experimental Therapeutics

Drug Transport and Resistance MechanismsComputational Drug Discovery Methods

Cited by 92

In Vitro Evaluation of Photosensitivity Risk Related to Genetic Polymorphisms of Human ABC Transporter ABCG2 and Inhibition by Drugs

Tamura, A., Onishi, Y., An, R., Koshiba, S., Wakabayashi, K., Hoshijima, K., Priebe, W., Yoshida, T., Kometani, S., Matsubara, T., et al. (2007) · Drug Metabolism and Pharmacokinetics

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

Cited by 72

Human ABC Transporter ABCG2 in Xenobiotic Protection and Redox Biology

Wakabayashi, K., Tamura, A., Saito, H., Onishi, Y., & Ishikawa, T. (2006) · Drug Metabolism Reviews

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

Cited by 66

Enhanced expression of coproporphyrinogen oxidase in malignant brain tumors: CPOX expression and 5-ALA-induced fluorescence

Takahashi, K., Ikeda, N., Nonoguchi, N., Kajimoto, Y., Miyatake, S.-I., Hagiya, Y., Ogura, S.-I., Nakagawa, H., Ishikawa, T., & Kuroiwa, T. (2011) · Neuro-Oncology

Photodynamic Therapy Research StudiesPorphyrin Metabolism and Disorders

Cited by 46

Cellular Phototoxicity Evoked Through the Inhibition of Human ABC Transporter ABCG2 by Cyclin-dependent Kinase Inhibitors In vitro

An, R., Hagiya, Y., Tamura, A., Li, S., Saito, H., Tokushima, D., & Ishikawa, T. (2009) · Pharmaceutical Research

Drug Transport and Resistance MechanismsPhotodynamic Therapy Research Studies

Cited by 34

Transporter-Mediated Drug Interaction Strategy for 5-Aminolevulinic Acid (ALA)-Based Photodynamic Diagnosis of Malignant Brain Tumor: Molecular Design of ABCG2 Inhibitors

Ishikawa, T., Takahashi, K., Ikeda, N., Kajimoto, Y., Hagiya, Y., Ogura, S.-I., Miyatake, S.-I., & Kuroiwa, T. (2011) · Pharmaceutics

Drug Transport and Resistance MechanismsPhotodynamic Therapy Research Studies

Cited by 34

Drug-induced phototoxicity evoked by inhibition of human ABC transporter ABCG2: development of in vitro high-speed screening systems

Tamura, A., An, R., Hagiya, Y., Hoshijima, K., Yoshida, T., Mikuriya, K., & Ishikawa, T. (2008) · Expert Opinion on Drug Metabolism & Toxicology

Drug Transport and Resistance MechanismsPhotodynamic Therapy Research Studies

Cited by 16

Emerging New Technology: QSAR Analysis and MO Calculation to Characterize Interactions of Protein Kinase Inhibitors with the Human ABC Transporter, ABCG2 (BCRP)

Saito, H., An, R., Hirano, H., & Ishikawa, T. (2010) · Drug Metabolism and Pharmacokinetics

Drug Transport and Resistance MechanismsComputational Drug Discovery Methods

Cited by 7