Housseau, Franck

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

Le, D. T., Durham, J. N., Smith, K. N., Wang, H., Bartlett, B. R., Aulakh, L. K., Lu, S., Kemberling, H., Wilt, C., Luber, B. S., et al. (2017) · Science

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 6,645

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

Wu, S., Rhee, K.-J., Albesiano, E., Rabizadeh, S., Wu, X., Yen, H.-R., Huso, D. L., Brancati, F. L., Wick, E., McAllister, F., et al. (2009) · Nature Medicine

Gut microbiota and healthT-cell and B-cell Immunology

Cited by 1,812

The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints

Llosa, N. J., Cruise, M., Tam, A., Wicks, E. C., Hechenbleikner, E. M., Taube, J. M., Blosser, R. L., Fan, H., Wang, H., Luber, B. S., et al. (2015) · Cancer Discovery

Cancer Immunotherapy and BiomarkersGenetic factors in colorectal cancer

Cited by 1,487

Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria

Dejea, C. M., Fathi, P., Craig, J. M., Boleij, A., Taddese, R., Geis, A. L., Wu, X., DeStefano Shields, C. E., Hechenbleikner, E. M., Huso, D. L., et al. (2018) · Science

Gut microbiota and healthBacterial biofilms and quorum sensing

Cited by 1,105

Microbiota organization is a distinct feature of proximal colorectal cancers

Dejea, C. M., Wick, E. C., Hechenbleikner, E. M., White, J. R., Mark Welch, J. L., Rossetti, B. J., Peterson, S. N., Snesrud, E. C., Borisy, G. G., Lazarev, M., et al. (2014) · Proceedings of the National Academy of Sciences

Gut microbiota and healthBacterial biofilms and quorum sensing

Cited by 700

Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells

Sadtler, K., Estrellas, K., Allen, B. W., Wolf, M. T., Fan, H., Tam, A. J., Patel, C. H., Luber, B. S., Wang, H., Wagner, K. R., et al. (2016) · Science

Wound Healing and TreatmentsTissue Engineering and Regenerative Medicine

Cited by 605

Oncogenic Kras activates a hematopoietic-to-epithelial IL-17 signaling axis in preinvasive pancreatic neoplasia

McAllister, F., Bailey, J. M., Alsina, J., Nirschl, C. J., Sharma, R., Fan, H., Rattigan, Y., Roeser, J. C., Lankapalli, R. H., Zhang, H., et al. (2014) · Cancer Cell

Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment

Cited by 405

Epigenetic therapy inhibits metastases by disrupting premetastatic niches

Lu, Z., Zou, J., Li, S., Topper, M. J., Tao, Y., Zhang, H., Jiao, X., Xie, W., Kong, X., Vaz, M., et al. (2020) · Nature

Immune cells in cancerCancer Cells and Metastasis

Cited by 330

IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis

Faust, H. J., Zhang, H., Han, J., Wolf, M. T., Jeon, O. H., Sadtler, K., Peña, A. N., Chung, L., Maestas, D. R., Tam, A. J., et al. (2020) · Journal of Clinical Investigation

Osteoarthritis Treatment and MechanismsTelomeres, Telomerase, and Senescence

Cited by 260

Divergent immune responses to synthetic and biological scaffolds

Sadtler, K., Wolf, M. T., Ganguly, S., Moad, C. A., Chung, L., Majumdar, S., Housseau, F., Pardoll, D. M., & Elisseeff, J. H. (2019) · Biomaterials

Wound Healing and TreatmentsTissue Engineering and Regenerative Medicine

Cited by 256

Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic

Tomkovich, S., Dejea, C. M., Winglee, K., Drewes, J. L., Chung, L., Housseau, F., Pope, J. L., Gauthier, J., Sun, X., Mühlbauer, M., et al. (2019) · Journal of Clinical Investigation

Gut microbiota and healthBacterial biofilms and quorum sensing

Cited by 209

Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis

Housseau, F., Wu, S., Wick, E. C., Fan, H., Wu, X., Llosa, N. J., Smith, K. N., Tam, A., Ganguly, S., Wanyiri, J. W., et al. (2016) · Cancer Research

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 143

Pathways of immune exclusion in metastatic osteosarcoma are associated with inferior patient outcomes

Ligon, J. A., Choi, W., Cojocaru, G., Fu, W., Hsiue, E. H.-C., Oke, T. F., Siegel, N., Fong, M. H., Ladle, B., Pratilas, C. A., et al. (2021) · Journal for ImmunoTherapy of Cancer

Cancer Immunotherapy and BiomarkersSarcoma Diagnosis and Treatment

Cited by 124

Sporadic colorectal cancer: microbial contributors to disease prevention, development and therapy

Drewes, J. L., Housseau, F., & Sears, C. L. (2016) · British Journal of Cancer

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 121

Transfer learning in a biomaterial fibrosis model identifies in vivo senescence heterogeneity and contributions to vascularization and matrix production across species and diverse pathologies

Cherry, C., Andorko, J. I., Krishnan, K., Mejías, J. C., Nguyen, H. H., Stivers, K. B., Gray-Gaillard, E. F., Ruta, A., Han, J., Hamada, N., et al. (2023) · GeroScience

Telomeres, Telomerase, and SenescenceSingle-cell and spatial transcriptomics

Cited by 66

Murine fecal microbiota transfer models selectively colonize human microbes and reveal transcriptional programs associated with response to neoadjuvant checkpoint inhibitors

Shaikh, F. Y., Gills, J. J., Mohammad, F., White, J. R., Stevens, C. M., Ding, H., Fu, J., Tam, A., Blosser, R. L., Domingue, J. C., et al. (2022) · Cancer Immunology, Immunotherapy

Cancer Immunotherapy and BiomarkersGut microbiota and health

Cited by 30

Age‐associated Senescent – T Cell Signaling Promotes Type 3 Immunity that Inhibits the Biomaterial Regenerative Response

Han, J., Cherry, C., Mejías, J. C., Krishnan, K., Ruta, A., Maestas, D. R., Peña, A. N., Nguyen, H. H., Nagaraj, S., Yang, B., et al. (2024) · Advanced Materials

Tissue Engineering and Regenerative MedicineWound Healing and Treatments

Cited by 17