Brakhage, Axel A.

Stress-Induced Changes in the Lipid Microenvironment of β-(1,3)- d -Glucan Synthase Cause Clinically Important Echinocandin Resistance in Aspergillus fumigatus

Satish, S., Jiménez-Ortigosa, C., Zhao, Y., Lee, M. H., Dolgov, E., Krüger, T., Park, S., Denning, D. W., Kniemeyer, O., Brakhage, A. A., et al. (2019) · mBio

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 64

Melanin targets LC3-associated phagocytosis (LAP): A novel pathogenetic mechanism in fungal disease

Chamilos, G., Akoumianaki, T., Kyrmizi, I., Brakhage, A., Beauvais, A., & Latge, J.-P. (2016) · Autophagy

Autophagy in Disease and TherapyAntifungal resistance and susceptibility

Cited by 46

Identification and Characterization of a Novel Aspergillus fumigatus Rhomboid Family Putative Protease, RbdA, Involved in Hypoxia Sensing and Virulence

Vaknin, Y., Hillmann, F., Iannitti, R., Ben Baruch, N., Sandovsky-Losica, H., Shadkchan, Y., Romani, L., Brakhage, A., Kniemeyer, O., & Osherov, N. (2016) · Infection and Immunity

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 45

Functional analysis of the Aspergillus fumigatus kinome reveals a DYRK kinase involved in septal plugging is a novel antifungal drug target

Rhijn, N. V., Zhao, C., Al-Furaji, N., Storer, I., Valero, C., Gago, S., Chown, H., Baldin, C., Fortune-Grant, R., Shuraym, H. B., et al. (2023) · Nature Communications

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 30

Functional analysis of the Aspergillus fumigatus kinome identifies a druggable DYRK kinase that regulates septal plugging

van Rhijn, N., Zhao, C., Al-Furaiji, N., Storer, I. S. R., Valero, C., Gago, S., Chown, H., Baldin, C., Grant, R.-F., Bin Shuraym, H., et al. (2024) · Nature Communications

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 30

The novel globin protein fungoglobin is involved in low oxygen adaptation of Aspergillus fumigatus

Hillmann, F., Linde, J., Beckmann, N., Cyrulies, M., Strassburger, M., Heinekamp, T., Haas, H., Guthke, R., Kniemeyer, O., & Brakhage, A. A. (2014) · Molecular Microbiology

Fungal and yeast genetics researchHemoglobin structure and function

Cited by 26

The hypoxia‐induced dehydrogenase HorA is required for coenzyme Q10 biosynthesis, azole sensitivity and virulence of Aspergillus fumigatus

Kroll, K., Shekhova, E., Mattern, D. J., Thywissen, A., Jacobsen, I. D., Strassburger, M., Heinekamp, T., Shelest, E., Brakhage, A. A., & Kniemeyer, O. (2016) · Molecular Microbiology

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 22