Brakhage, Axel A.

Surface hydrophobin prevents immune recognition of airborne fungal spores

Aimanianda, V., Bayry, J., Bozza, S., Kniemeyer, O., Perruccio, K., Elluru, S. R., Clavaud, C., Paris, S., Brakhage, A. A., Kaveri, S. V., et al. (2009) · Nature

Fungal Infections and StudiesAntifungal resistance and susceptibility

Cited by 792

Biosynthesis of fungal melanins and their importance for human pathogenic fungi

Langfelder, K., Streibel, M., Jahn, B., Haase, G., & Brakhage, A. A. (2003) · Fungal Genetics and Biology

Fungal and yeast genetics researchFungal Infections and Studies

Cited by 634

Human Anti-fungal Th17 Immunity and Pathology Rely on Cross-Reactivity against Candida albicans

Bacher, P., Hohnstein, T., Beerbaum, E., Röcker, M., Blango, M. G., Kaufmann, S., Röhmel, J., Eschenhagen, P., Grehn, C., Seidel, K., et al. (2019) · Cell

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 473

The akuB KU80 Mutant Deficient for Nonhomologous End Joining Is a Powerful Tool for Analyzing Pathogenicity in Aspergillus fumigatus

da Silva Ferreira, M. E., Kress, M. R. V. Z., Savoldi, M., Goldman, M. H. S., Härtl, A., Heinekamp, T., Brakhage, A. A., & Goldman, G. H. (2006) · Eukaryotic Cell

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 403

Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans

Bacher, P., Heinrich, F., Stervbo, U., Nienen, M., Vahldieck, M., Iwert, C., Vogt, K., Kollet, J., Babel, N., Sawitzki, B., et al. (2016) · Cell

T-cell and B-cell ImmunologyAllergic Rhinitis and Sensitization

Cited by 319

HapX-Mediated Adaption to Iron Starvation Is Crucial for Virulence of Aspergillus fumigatus

Schrettl, M., Beckmann, N., Varga, J., Heinekamp, T., Jacobsen, I. D., Jöchl, C., Moussa, T. A., Wang, S., Gsaller, F., Blatzer, M., et al. (2010) · PLoS Pathogens

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 284

Interaction of HapX with the CCAAT‐binding complex—a novel mechanism of gene regulation by iron

Hortschansky, P., Eisendle, M., Al‐Abdallah, Q., Schmidt, A. D., Bergmann, S., Thön, M., Kniemeyer, O., Abt, B., Seeber, B., Werner, E. R., et al. (2007) · The EMBO Journal

Fungal and yeast genetics researchIron Metabolism and Disorders

Cited by 232

The Aspergillus fumigatus Transcriptional Regulator AfYap1 Represents the Major Regulator for Defense against Reactive Oxygen Intermediates but Is Dispensable for Pathogenicity in an Intranasal Mouse Infection Model

Lessing, F., Kniemeyer, O., Wozniok, I., Loeffler, J., Kurzai, O., Haertl, A., & Brakhage, A. A. (2007) · Eukaryotic Cell

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 221

Aspergillus Cell Wall Melanin Blocks LC3-Associated Phagocytosis to Promote Pathogenicity

Akoumianaki, T., Kyrmizi, I., Valsecchi, I., Gresnigt, M. S., Samonis, G., Drakos, E., Boumpas, D., Muszkieta, L., Prevost, M.-C., Kontoyiannis, D. P., et al. (2016) · Cell Host & Microbe

Autophagy in Disease and TherapyAntifungal resistance and susceptibility

Cited by 218

Aspergillus fumigatus melanins: interference with the host endocytosis pathway and impact on virulence

Heinekamp, T., Thywißen, A., Macheleidt, J., Keller, S., Valiante, V., & Brakhage, A. A. (2013) · Frontiers in Microbiology

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 216

Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus

Stappers, M. H. T., Clark, A. E., Aimanianda, V., Bidula, S., Reid, D. M., Asamaphan, P., Hardison, S. E., Dambuza, I. M., Valsecchi, I., Kerscher, B., et al. (2018) · Nature

Antifungal resistance and susceptibilityImmune Response and Inflammation

Cited by 200

Antigen-Reactive T Cell Enrichment for Direct, High-Resolution Analysis of the Human Naive and Memory Th Cell Repertoire

Bacher, P., Schink, C., Teutschbein, J., Kniemeyer, O., Assenmacher, M., Brakhage, A. A., & Scheffold, A. (2013) · The Journal of Immunology

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 173

Deletion of the gliP gene of Aspergillus fumigatus results in loss of gliotoxin production but has no effect on virulence of the fungus in a low‐dose mouse infection model

Kupfahl, C., Heinekamp, T., Geginat, G., Ruppert, T., Härtl, A., Hof, H., & Brakhage, A. A. (2006) · Molecular Microbiology

Microbial Natural Products and BiosynthesisAntifungal resistance and susceptibility

Cited by 157

A New Approach to Drug Discovery: High-Throughput Screening of Microbial Natural Extracts against Aspergillus fumigatus Using Resazurin

Monteiro, M. C., de la Cruz, M., Cantizani, J., Moreno, C., Tormo, J. R., Mellado, E., De Lucas, J. R., Asensio, F., Valiante, V., Brakhage, A. A., et al. (2012) · SLAS Discovery

Antifungal resistance and susceptibilityMicrobial Natural Products and Biosynthesis

Cited by 144

The MAP kinase MpkA controls cell wall integrity, oxidative stress response, gliotoxin production and iron adaptation in Aspergillus fumigatus

Jain, R., Valiante, V., Remme, N., Docimo, T., Heinekamp, T., Hertweck, C., Gershenzon, J., Haas, H., & Brakhage, A. A. (2011) · Molecular Microbiology

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 140

Surface Structure Characterization of Aspergillus fumigatus Conidia Mutated in the Melanin Synthesis Pathway and Their Human Cellular Immune Response

Bayry, J., Beaussart, A., Dufrêne, Y. F., Sharma, M., Bansal, K., Kniemeyer, O., Aimanianda, V., Brakhage, A. A., Kaveri, S. V., Kwon-Chung, K. J., et al. (2014) · Infection and Immunity

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 137

Analysis of the Aspergillus fumigatus Proteome Reveals Metabolic Changes and the Activation of the Pseurotin A Biosynthesis Gene Cluster in Response to Hypoxia

Vödisch, M., Scherlach, K., Winkler, R., Hertweck, C., Braun, H.-P., Roth, M., Haas, H., Werner, E. R., Brakhage, A. A., & Kniemeyer, O. (2011) · Journal of Proteome Research

Fungal and yeast genetics researchMicrobial Natural Products and Biosynthesis

Cited by 128

Deletion of the α-(1,3)-Glucan Synthase Genes Induces a Restructuring of the Conidial Cell Wall Responsible for the Avirulence of Aspergillus fumigatus

Beauvais, A., Bozza, S., Kniemeyer, O., Formosa, C., Balloy, V., Henry, C., Roberson, R. W., Dague, E., Chignard, M., Brakhage, A. A., et al. (2013) · PLoS Pathogens

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 127

Interference of Aspergillus fumigatus with the immune response

Heinekamp, T., Schmidt, H., Lapp, K., Pähtz, V., Shopova, I., Köster-Eiserfunke, N., Krüger, T., Kniemeyer, O., & Brakhage, A. A. (2015) · Seminars in Immunopathology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 123

Functional characterization of the Aspergillus fumigatus calcineurin

Ferreira, M. E. D. S., Heinekamp, T., Härtl, A., Brakhage, A. A., Semighini, C. P., Harris, S. D., Savoldi, M., de Gouvêa, P. F., Goldman, M. H. D. S., & Goldman, G. H. (2007) · Fungal Genetics and Biology

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 121

Integrative analysis of the heat shock response in Aspergillus fumigatus

Albrecht, D., Guthke, R., Brakhage, A. A., & Kniemeyer, O. (2010) · BMC Genomics

Fungal and yeast genetics researchHeat shock proteins research

Cited by 105

Induction of Mitochondrial Reactive Oxygen Species Production by Itraconazole, Terbinafine, and Amphotericin B as a Mode of Action against Aspergillus fumigatus

Shekhova, E., Kniemeyer, O., & Brakhage, A. A. (2017) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 105

Calcium sequestration by fungal melanin inhibits calcium–calmodulin signalling to prevent LC3-associated phagocytosis

Kyrmizi, I., Ferreira, H., Carvalho, A., Figueroa, J. A. L., Zarmpas, P., Cunha, C., Akoumianaki, T., Stylianou, K., Deepe, G. S., Samonis, G., et al. (2018) · Nature Microbiology

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 96

Proteome Analysis Reveals the Conidial Surface Protein CcpA Essential for Virulence of the Pathogenic Fungus Aspergillus fumigatus

Voltersen, V., Blango, M. G., Herrmann, S., Schmidt, F., Heinekamp, T., Strassburger, M., Krüger, T., Bacher, P., Lother, J., Weiss, E., et al. (2018) · mBio

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 71