Freed, Eric O.

HIV-1 Gag proteins: diverse functions in the virus life cycle

Freed, E. O. (1998) · Virology

HIV Research and TreatmentT-cell and Retrovirus Studies

Cited by 717

HIV-1 assembly, release and maturation

Freed, E. O. (2015) · Nature Reviews Microbiology

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 654

Phosphatidylinositol (4,5) bisphosphate regulates HIV-1 Gag targeting to the plasma membrane

Ono, A., Ablan, S. D., Lockett, S. J., Nagashima, K., & Freed, E. O. (2004) · Proceedings of the National Academy of Sciences

HIV Research and TreatmentCellular transport and secretion

Cited by 553

p6Gag is required for particle production from full-length human immunodeficiency virus type 1 molecular clones expressing protease

Huang, M., Orenstein, J. M., Martin, M. A., & Freed, E. O. (1995) · Journal of Virology

HIV Research and TreatmentT-cell and Retrovirus Studies

Cited by 486

The late domain of human immunodeficiency virus Type 1 p6 promotes virus release in a cell type-dependent manner

Demirov, D. G., Orenstein, J. M., & Freed, E. O. (2002) · Journal of Virology

HIV Research and TreatmentT-cell and Retrovirus Studies

Cited by 201

Human immunodeficiency virus type 1 assembly, release, and maturation

Adamson, C. S., & Freed, E. O. (2007) · Advances in Pharmacology

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 179

Ion-abrasion scanning electron microscopy reveals surface-connected tubular conduits in HIV-infected macrophages

Bennett, A. E., Narayan, K., Shi, D., Hartnell, L. M., Gousset, K., He, H., Lowekamp, B. C., Yoo, T. S., Bliss, D., Freed, E. O., et al. (2009) · PLoS Pathogens

HIV Research and TreatmentAdvanced Electron Microscopy Techniques and Applications

Cited by 163

Structure of the myristylated human immunodeficiency virus type 2 matrix protein and the role of phosphatidylinositol-(4,5)-bisphosphate in membrane targeting

Saad, J. S., Ablan, S. D., Ghanam, R. H., Kim, A., Andrews, K., Nagashima, K., Soheilian, F., Freed, E. O., & Summers, M. F. (2008) · Journal of Molecular Biology

HIV Research and TreatmentLipid Membrane Structure and Behavior

Cited by 95

Structural and functional insights into the HIV-1 maturation inhibitor binding pocket

Waki, K., Durell, S. R., Soheilian, F., Nagashima, K., Butler, S. L., & Freed, E. O. (2012) · PLoS Pathogens

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 71

Myosin-X is essential to the intercellular spread of HIV-1 Nef through tunneling nanotubes

Uhl, J., Gujarathi, S., Waheed, A. A., Gordon, A., Freed, E. O., & Gousset, K. (2019) · Journal of Cell Communication and Signaling

HIV Research and TreatmentCellular transport and secretion

Cited by 57

Impact of human immunodeficiency virus Type 1 resistance to protease inhibitors on evolution of resistance to the maturation inhibitor Bevirimat (PA-457)

Adamson, C. S., Waki, K., Ablan, S. D., Salzwedel, K., & Freed, E. O. (2009) · Journal of Virology

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 48

Genomic tagging of endogenous human ESCRT-I complex preserves ESCRT-mediated membrane-remodeling functions

Hoffman, H. K., Fernandez, M. V., Groves, N. S., Freed, E. O., & van Engelenburg, S. B. (2019) · Journal of Biological Chemistry

Cellular transport and secretionUbiquitin and proteasome pathways

Cited by 28

Structural basis of HIV-1 maturation inhibitor binding and activity

Sarkar, S., Zadrozny, K. K., Zadorozhnyi, R., Russell, R. W., Quinn, C. M., Kleinpeter, A., Ablan, S., Meshkin, H., Perilla, J. R., Freed, E. O., et al. (2023) · Nature Communications

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 28