Abramov, Andrey Y.

The emerging role of Nrf2 in mitochondrial function

Dinkova-Kostova, A. T., & Abramov, A. Y. (2015) · Free Radical Biology and Medicine

Genomics, phytochemicals, and oxidative stressMitochondrial Function and Pathology

Cited by 983

Role of mitochondrial ROS in the brain: from physiology to neurodegeneration

Angelova, P. R., & Abramov, A. Y. (2018) · FEBS Letters

Mitochondrial Function and PathologyRedox biology and oxidative stress

Cited by 789

PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death

Gandhi, S., Wood-Kaczmar, A., Yao, Z., Plun-Favreau, H., Deas, E., Klupsch, K., Downward, J., Latchman, D. S., Tabrizi, S. J., Wood, N. W., et al. (2009) · Molecular Cell

Parkinson's Disease Mechanisms and TreatmentsMitochondrial Function and Pathology

Cited by 682

β-Amyloid Peptides Induce Mitochondrial Dysfunction and Oxidative Stress in Astrocytes and Death of Neurons through Activation of NADPH Oxidase

Abramov, A. Y., Canevari, L., & Duchen, M. R. (2004) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsMitochondrial Function and Pathology

Cited by 587

α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease

Ludtmann, M. H. R., Angelova, P. R., Horrocks, M. H., Choi, M. L., Rodrigues, M., Baev, A. Y., Berezhnov, A. V., Yao, Z., Little, D., Banushi, B., et al. (2018) · Nature Communications

Parkinson's Disease Mechanisms and TreatmentsMitochondrial Function and Pathology

Cited by 513

Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal

Sun, W.-Y., Tyurin, V. A., Mikulska-Ruminska, K., Shrivastava, I. H., Anthonymuthu, T. S., Zhai, Y.-J., Pan, M.-H., Gong, H.-B., Lu, D.-H., Sun, J., et al. (2021) · Nature Chemical Biology

Ferroptosis and cancer prognosisNeurological diseases and metabolism

Cited by 337

Changes in Intracellular Calcium and Glutathione in Astrocytes as the Primary Mechanism of Amyloid Neurotoxicity

Abramov, A. Y., Canevari, L., & Duchen, M. R. (2003) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 337

Role of DJ-1 in the mechanism of pathogenesis of Parkinson's disease

Dolgacheva, L. P., Berezhnov, A. V., Fedotova, E. I., Zinchenko, V. P., & Abramov, A. Y. (2019) · Journal of Bioenergetics and Biomembranes

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 254

Calcium signals induced by amyloid β peptide and their consequences in neurons and astrocytes in culture

Abramov, A. Y., Canevari, L., & Duchen, M. R. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 223

Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS

Hall, C. E., Yao, Z., Choi, M., Tyzack, G. E., Serio, A., Luisier, R., Harley, J., Preza, E., Arber, C., Crisp, S. J., et al. (2017) · Cell Reports

Amyotrophic Lateral Sclerosis ResearchPluripotent Stem Cells Research

Cited by 179

Interaction of Mitochondrial Calcium and ROS in Neurodegeneration

Baev, A. Y., Vinokurov, A. Y., Novikova, I. N., Dremin, V. V., Potapova, E. V., & Abramov, A. Y. (2022) · Cells

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 162

Pathogenic VCP Mutations Induce Mitochondrial Uncoupling and Reduced ATP Levels

Bartolome, F., Wu, H.-C., Burchell, V. S., Preza, E., Wray, S., Mahoney, C. J., Fox, N. C., Calvo, A., Canosa, A., Moglia, C., et al. (2013) · Neuron

Mitochondrial Function and PathologyAmyotrophic Lateral Sclerosis Research

Cited by 156

Mitochondrial energy imbalance and lipid peroxidation cause cell death in Friedreich’s ataxia

Abeti, R., Parkinson, M. H., Hargreaves, I. P., Angelova, P. R., Sandi, C., Pook, M. A., Giunti, P., & Abramov, A. Y. (2016) · Cell Death & Disease

Mitochondrial Function and PathologyGenetic Neurodegenerative Diseases

Cited by 133

Deletion of the von Hippel–Lindau gene in pancreatic β cells impairs glucose homeostasis in mice

Cantley, J., Selman, C., Shukla, D., Abramov, A. Y., Forstreuter, F., Esteban, M. A., Claret, M., Lingard, S. J., Clements, M., Harten, S. K., et al. (2008) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 127

Insoluble tau aggregates induce neuronal death through modification of membrane ion conductance, activation of voltage‐gated calcium channels and NADPH oxidase

Esteras, N., Kundel, F., Amodeo, G. F., Pavlov, E. V., Klenerman, D., & Abramov, A. Y. (2021) · The FEBS Journal

Alzheimer's disease research and treatmentsAldose Reductase and Taurine

Cited by 78

Deficiency of Parkinson’s disease-related gene Fbxo7 is associated with impaired mitochondrial metabolism by PARP activation

Delgado-Camprubi, M., Esteras, N., Soutar, M. P., Plun-Favreau, H., & Abramov, A. Y. (2017) · Cell Death & Differentiation

Parkinson's Disease Mechanisms and TreatmentsMitochondrial Function and Pathology

Cited by 71

A Critical Role for Purinergic Signalling in the Mechanisms Underlying Generation of BOLD fMRI Responses

Wells, J. A., Christie, I. N., Hosford, P. S., Huckstepp, R. T. R., Angelova, P. R., Vihko, P., Cork, S. C., Abramov, A. Y., Teschemacher, A. G., Kasparov, S., et al. (2015) · The Journal of Neuroscience

Adenosine and Purinergic SignalingAdvanced MRI Techniques and Applications

Cited by 57

Interplay of mitochondrial calcium signalling and reactive oxygen species production in the brain

Angelova, P. R., & Abramov, A. Y. (2024) · Biochemical Society Transactions

Mitochondrial Function and PathologyRedox biology and oxidative stress

Cited by 56

Adrenaline induces calcium signal in astrocytes and vasoconstriction via activation of monoamine oxidase

Novikova, I. N., Manole, A., Zherebtsov, E. A., Stavtsev, D. D., Vukolova, M. N., Dunaev, A. V., Angelova, P. R., & Abramov, A. Y. (2020) · Free Radical Biology and Medicine

Neuroscience and Neuropharmacology ResearchRedox biology and oxidative stress

Cited by 42

Age-related Changes in the Energy of Human Mesenchymal Stem Cells

Barilani, M., Lovejoy, C., Piras, R., Abramov, A. Y., Lazzari, L., & Angelova, P. R. (2022) · Journal of Cellular Physiology

Mitochondrial Function and PathologyMesenchymal stem cell research

Cited by 31