Houslay, Miles D.

DISC1 and PDE4B Are Interacting Genetic Factors in Schizophrenia That Regulate cAMP Signaling

Millar, J. K., Pickard, B. S., Mackie, S., James, R., Christie, S., Buchanan, S. R., Malloy, M. P., Chubb, J. E., Huston, E., Baillie, G. S., et al. (2005) · Science

Phosphodiesterase function and regulationSchizophrenia research and treatment

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Behavioral phenotypes of Disc1 missense mutations in mice

Clapcote, S. J., Lipina, T. V., Millar, J. K., Mackie, S., Christie, S., Ogawa, F., Lerch, J. P., Trimble, K., Uchiyama, M., Sakuraba, Y., et al. (2007) · Neuron

Schizophrenia research and treatmentTreatment of Major Depression

Cited by 526

Sleep deprivation impairs cAMP signalling in the hippocampus

Vecsey, C. G., Baillie, G. S., Jaganath, D., Havekes, R., Daniels, A., Wimmer, M., Huang, T., Brown, K. M., Li, X.-Y., Descalzi, G., et al. (2009) · Nature

Sleep and Wakefulness ResearchSleep and Work-Related Fatigue

Cited by 454

Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

Hayashi-Takagi, A., Takaki, M., Graziane, N., Seshadri, S., Murdoch, H., Dunlop, A. J., Makino, Y., Seshadri, A. J., Ishizuka, K., Srivastava, D. P., et al. (2010) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchSchizophrenia research and treatment

Cited by 399

Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1

Havekes, R., Park, A. J., Tudor, J. C., Luczak, V. G., Hansen, R. T., Ferri, S. L., Bruinenberg, V. M., Poplawski, S. G., Day, J. P., Aton, S. J., et al. (2016) · eLife

Sleep and Wakefulness ResearchMemory and Neural Mechanisms

Cited by 292

EPAC and PKA allow cAMP dual control over DNA-PK nuclear translocation

Huston, E., Lynch, M. J., Mohamed, A., Collins, D. M., Hill, E. V., MacLeod, R., Krause, E., Baillie, G. S., & Houslay, M. D. (2008) · Proceedings of the National Academy of Sciences

Protein Kinase Regulation and GTPase SignalingPhosphodiesterase function and regulation

Cited by 129

Inferring signaling pathway topologies from multiple perturbation measurements of specific biochemical species

Xu, T.-R., Vyshemirsky, V., Gormand, A., von Kriegsheim, A., Girolami, M., Baillie, G. S., Ketley, D., Dunlop, A. J., Milligan, G., Houslay, M. D., et al. (2010) · Science Signaling

Gene Regulatory Network AnalysisBioinformatics and Genomic Networks

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The role of ventral striatal cAMP signaling in stress-induced behaviors

Plattner, F., Hayashi, K., Hernández, A., Benavides, D. R., Tassin, T. C., Tan, C., Day, J., Fina, M. W., Yuen, E. Y., Yan, Z., et al. (2015) · Nature Neuroscience

Phosphodiesterase function and regulationNeurotransmitter Receptor Influence on Behavior

Cited by 94

Phosphorylation of cAMP-specific PDE4A5 (phosphodiesterase-4A5) by MK2 (MAPKAPK2) attenuates its activation through protein kinase A phosphorylation

MacKenzie, K. F., Wallace, D. A., Hill, E. V., Anthony, D. F., Henderson, D. J. P., Houslay, D. M., Arthur, J. S. C., Baillie, G. S., & Houslay, M. D. (2011) · Biochemical Journal

Phosphodiesterase function and regulationProtein Tyrosine Phosphatases

Cited by 65