Luk, Kevin

Highly efficient therapeutic gene editing of human hematopoietic stem cells

Wu, Y., Zeng, J., Roscoe, B. P., Liu, P., Yao, Q., Lazzarotto, C. R., Clement, K., Cole, M. A., Luk, K., Baricordi, C., et al. (2019) · Nature Medicine

Hemoglobinopathies and Related DisordersCRISPR and Genetic Engineering

Cited by 515

Genome editing of HBG1 and HBG2 to induce fetal hemoglobin

Métais, J.-Y., Doerfler, P. A., Mayuranathan, T., Bauer, D. E., Fowler, S. C., Hsieh, M. M., Katta, V., Keriwala, S., Lazzarotto, C. R., Luk, K., et al. (2019) · Blood Advances

Hemoglobinopathies and Related DisordersCRISPR and Genetic Engineering

Cited by 177

Evaluating and enhancing target specificity of gene-editing nucleases and deaminases

Kim, D., Luk, K., Wolfe, S. A., & Kim, J.-S. (2019) · Annual Review of Biochemistry

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 171

Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells

Nagpal, N., Wang, J., Zeng, J., Lo, E., Moon, D. H., Luk, K., Braun, R. O., Burroughs, L. M., Keel, S. B., Reilly, C., et al. (2020) · Cell Stem Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 105

Generation and application of endogenously floxed alleles for cell-specific knockout in zebrafish

Shin, M., Yin, H.-M., Shih, Y.-H., Nozaki, T., Portman, D., Toles, B., Kolb, A., Luk, K., Isogai, S., Ishida, K., et al. (2023) · Developmental Cell

Zebrafish Biomedical Research ApplicationsCRISPR and Genetic Engineering

Cited by 28