Baca, Sylvan C.

Mutational heterogeneity in cancer and the search for new cancer-associated genes

Lawrence, M. S., Stojanov, P., Polak, P., Kryukov, G. V., Cibulskis, K., Sivachenko, A., Carter, S. L., Stewart, C., Mermel, C. H., Roberts, S. A., et al. (2013) · Nature

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

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Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma

Perry, J. A., Kiezun, A., Tonzi, P., Van Allen, E. M., Carter, S. L., Baca, S. C., Cowley, G. S., Bhatt, A. S., Rheinbay, E., Pedamallu, C. S., et al. (2014) · Proceedings of the National Academy of Sciences

Sarcoma Diagnosis and TreatmentPI3K/AKT/mTOR signaling in cancer

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Machine learning for genetics-based classification and treatment response prediction in cancer of unknown primary

Moon, I., LoPiccolo, J., Baca, S. C., Sholl, L. M., Kehl, K. L., Hassett, M. J., Liu, D., Schrag, D., & Gusev, A. (2023) · Nature Medicine

Cancer Diagnosis and TreatmentCancer Genomics and Diagnostics

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CREB5 reprograms FOXA1 nuclear interactions to promote resistance to androgen receptor-targeting therapies

Hwang, J. H., Arafeh, R., Seo, J.-H., Baca, S. C., Ludwig, M., Arnoff, T. E., Sawyer, L., Richter, C., Tape, S., Bergom, H. E., et al. (2022) · eLife

Prostate Cancer Treatment and ResearchChromatin Remodeling and Cancer

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Structurally Oriented Classification of FOXA1 Alterations Identifies Prostate Cancers with Opposing Clinical Outcomes and Distinct Molecular and Immunologic Subtypes

Hwang, J., Likasitwatanakul, P., Deshmukh, S. K., Wu, S., Kwon, J. J., Toye, E., Moline, D., Evans, M. G., Elliott, A., Passow, R., et al. (2025) · Clinical Cancer Research

Prostate Cancer Treatment and ResearchChromatin Remodeling and Cancer

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TFXcan reveals transcription factor programs driving GWAS loci

Adeluwa, T., Salazar-Magaña, S., Sumner, S., Gona, S., Nyasimi, F., Carbonetto, P., Baca, S. C., Freedman, M., Gusev, A., Liu, B., et al. (2026) · Cell Genomics

Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics

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