Rüegg, Markus A.

Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy

Bentzinger, C. F., Romanino, K., Cloëtta, D., Lin, S., Mascarenhas, J. B., Oliveri, F., Xia, J., Casanova, E., Costa, C. F., Brink, M., et al. (2008) · Cell Metabolism

Muscle Physiology and DisordersPI3K/AKT/mTOR signaling in cancer

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Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

Gödel, M., Hartleben, B., Herbach, N., Liu, S., Zschiedrich, S., Lu, S., Debreczeni-Mór, A., Lindenmeyer, M. T., Rastaldi, M.-P., Hartleben, G., et al. (2011) · Journal of Clinical Investigation

Renal Diseases and GlomerulopathiesChronic Kidney Disease and Diabetes

Cited by 547

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

Inoki, K., Mori, H., Wang, J., Suzuki, T., Hong, S., Yoshida, S., Blattner, S. M., Ikenoue, T., Rüegg, M. A., Hall, M. N., et al. (2011) · Journal of Clinical Investigation

Renal Diseases and GlomerulopathiesChronic Kidney Disease and Diabetes

Cited by 538

Adipose-Specific Knockout of raptor Results in Lean Mice with Enhanced Mitochondrial Respiration

Polak, P., Cybulski, N., Feige, J. N., Auwerx, J., Rüegg, M. A., & Hall, M. N. (2008) · Cell Metabolism

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 480

Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy

Risson, V., Mazelin, L., Roceri, M., Sanchez, H., Moncollin, V., Corneloup, C., Richard-Bulteau, H., Vignaud, A., Baas, D., Defour, A., et al. (2009) · Journal of Cell Biology

Muscle Physiology and DisordersPI3K/AKT/mTOR signaling in cancer

Cited by 381

Sustained Activation of mTORC1 in Skeletal Muscle Inhibits Constitutive and Starvation-Induced Autophagy and Causes a Severe, Late-Onset Myopathy

Castets, P., Lin, S., Rion, N., Di Fulvio, S., Romanino, K., Guridi, M., Frank, S., Tintignac, L. A., Sinnreich, M., & Rüegg, M. A. (2013) · Cell Metabolism

Autophagy in Disease and TherapyMuscle Physiology and Disorders

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Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy

Bentzinger, C. F., Lin, S., Romanino, K., Castets, P., Guridi, M., Summermatter, S., Handschin, C., Tintignac, L. A., Hall, M. N., & Rüegg, M. A. (2013) · Skeletal Muscle

Muscle Physiology and DisordersMuscle metabolism and nutrition

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BDNF is a mediator of glycolytic fiber-type specification in mouse skeletal muscle

Delezie, J., Weihrauch, M., Maier, G., Tejero, R., Ham, D. J., Gill, J. F., Karrer-Cardel, B., Rüegg, M. A., Tabares, L., & Handschin, C. (2019) · Proceedings of the National Academy of Sciences

Muscle Physiology and DisordersNerve injury and regeneration

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Molecular and phenotypic analysis of rodent models reveals conserved and species-specific modulators of human sarcopenia

Börsch, A., Ham, D. J., Mittal, N., Tintignac, L. A., Migliavacca, E., Feige, J. N., Rüegg, M. A., & Zavolan, M. (2021) · Communications Biology

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 85

Differential localization and anabolic responsiveness of mTOR complexes in human skeletal muscle in response to feeding and exercise

Hodson, N., McGlory, C., Oikawa, S. Y., Jeromson, S., Song, Z., Rüegg, M. A., Hamilton, D. L., Phillips, S. M., & Philp, A. (2017) · American Journal of Physiology-Cell Physiology

Muscle metabolism and nutritionPI3K/AKT/mTOR signaling in cancer

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“Get the Balance Right”: Pathological Significance of Autophagy Perturbation in Neuromuscular Disorders

Castets, P., Frank, S., Sinnreich, M., & Rüegg, M. A. (2016) · Journal of Neuromuscular Diseases

Autophagy in Disease and TherapyMuscle Physiology and Disorders

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