Ma, Xiaolei

Desensitization of soluble guanylyl cyclase, the NO receptor, by S-nitrosylation

Sayed, N., Baskaran, P., Ma, X., van den Akker, F., & Beuve, A. (2007) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsReceptor Mechanisms and Signaling

Cited by 221

Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy

Bonazzi, S., d’Hennezel, E., Beckwith, R. E. J., Xu, L., Fazal, A., Magracheva, A., Ramesh, R., Cernijenko, A., Antonakos, B., Bhang, H.-E. C., et al. (2023) · Cell Chemical Biology

Protein Degradation and InhibitorsCancer Immunotherapy and Biomarkers

Cited by 167

A molecular glue degrader of the WIZ transcription factor for fetal hemoglobin induction

Ting, P. Y., Borikar, S., Kerrigan, J. R., Thomsen, N. M., Aghania, E., Hinman, A. E., Reyes, A., Pizzato, N., Fodor, B. D., Wu, F., et al. (2024) · Science

Hemoglobinopathies and Related DisordersProtein Degradation and Inhibitors

Cited by 97

Effects of allogeneic mesenchymal stem cell transplantation in the treatment of liver cirrhosis caused by autoimmune diseases

Liang, J., Zhang, H., Zhao, C., Wang, D., Ma, X., Zhao, S., Wang, S., Niu, L., & Sun, L. (2017) · International Journal of Rheumatic Diseases

Mesenchymal stem cell researchLiver Disease and Transplantation

Cited by 93

DNA-encoded library-enabled discovery of proximity-inducing small molecules

Mason, J. W., Chow, Y. T., Hudson, L., Tutter, A., Michaud, G., Westphal, M. V., Shu, W., Ma, X., Tan, Z. Y., Coley, C. W., et al. (2024) · Nature Chemical Biology

Protein Degradation and InhibitorsChemical Synthesis and Analysis

Cited by 83

A small-molecule VHL molecular glue degrader for cysteine dioxygenase 1

Tutter, A., Buckley, D., Golosov, A. A., Ma, X., Shu, W., McKay, D. J. J., Darsigny, V., Dovala, D., Beckwith, R., Solomon, J., et al. (2025) · Nature Chemical Biology

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 36

Structural and biophysical comparisons of the pomalidomide- and CC-220-induced interactions of SALL4 with cereblon

Ma, X., Leon, B., Ornelas, E., Dovala, D., Tandeske, L., Luu, C., Pardee, G., Widger, S., Solomon, J. M., Beckwith, R. E. J., et al. (2023) · Scientific Reports

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 21

Discovery and Optimization of First-in-Class Molecular Glue Degraders of the WIZ Transcription Factor for Fetal Hemoglobin Induction to Treat Sickle Cell Disease

Kerrigan, J. R., Thomsen, N. M., Cernijenko, A., Kochanek, S. E., Dewhurst, J., O’Brien, G., Ware, N. F., Sanchez, C. C., Manning, J. R., Ma, X., et al. (2024) · Journal of Medicinal Chemistry

Hemoglobinopathies and Related DisordersProtein Degradation and Inhibitors

Cited by 15

Discovery and structural characterization of a VHL-mediated molecular glue degrader targeting cysteine dioxygenase

Ma, X. (2021) · Acta Crystallographica Section A Foundations and Advances

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 2