McEwan, Iain J.

Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor.

Andersen, R. J., Mawji, N. R., Wang, J., Wang, G., Haile, S., Myung, J.-K., Watt, K., Tam, T., Yang, Y. C., Bañuelos, C. A., et al. (2010) · Cancer Cell

Prostate Cancer Treatment and ResearchEstrogen and related hormone effects

Cited by 503

Structure and function of steroid receptor AF1 transactivation domains: induction of active conformations

Lavery, D. N., & Mcewan, I. J. (2005) · Biochemical Journal

Estrogen and related hormone effectsProtein Structure and Dynamics

Cited by 227

Molecular mechanisms of androgen receptor-mediated gene regulation: structure-function analysis of the AF-1 domain

McEwan, I. J. (2004) · Endocrine-related cancer

Prostate Cancer Treatment and ResearchEstrogen and related hormone effects

Cited by 156

Conformational Analysis of the Androgen Receptor Amino-terminal Domain Involved in Transactivation

Reid, J., Kelly, S. M., Watt, K., Price, N. C., & McEwan, I. J. (2002) · Journal of Biological Chemistry

Protein Structure and DynamicsProstate Cancer Treatment and Research

Cited by 143

Allosteric Modulators of Steroid Hormone Receptors: Structural Dynamics and Gene Regulation

Kumar, R., & McEwan, I. J. (2012) · Endocrine Reviews

Estrogen and related hormone effectsProtein Structure and Dynamics

Cited by 135

Regulation of the androgen receptor by SET9-mediated methylation.

Gaughan, L., Stockley, J., Wang, N., McCracken, S. R. C., Treumann, A., Armstrong, K., Shaheen, F., Watt, K., McEwan, I. J., Wang, C., et al. (2011) · Nucleic Acids Research

Prostate Cancer Treatment and ResearchCancer-related gene regulation

Cited by 127

Induced α-Helix Structure in AF1 of the Androgen Receptor upon Binding Transcription Factor TFIIF

Kumar, R., Betney, R., Li, J., Thompson, E. B., & McEwan, I. J. (2004) · Biochemistry

Protein Structure and DynamicsReceptor Mechanisms and Signaling

Cited by 107