Machius, Mischa

Artificial ligand binding within the HIF2α PAS-B domain of the HIF2 transcription factor

Scheuermann, T. H., Tomchick, D. R., Machius, M., Guo, Y., Bruick, R. K., & Gardner, K. H. (2009) · Proceedings of the National Academy of Sciences

Cancer, Hypoxia, and MetabolismHemoglobin structure and function

Cited by 301

Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis

Shin, O.-H., Lu, J., Rhee, J.-S., Tomchick, D. R., Pang, Z. P., Wojcik, S. M., Camacho-Perez, M., Brose, N., Machius, M., Rizo, J., et al. (2010) · Nature Structural & Molecular Biology

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 243

Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1

Yu, B., Martins, I. R. S., Li, P., Amarasinghe, G. K., Umetani, J., Fernandez-Zapico, M. E., Billadeau, D. D., Machius, M., Tomchick, D. R., & Rosen, M. K. (2010) · Cell

Protein Kinase Regulation and GTPase SignalingProtein Structure and Dynamics

Cited by 156

Structural Basis for a Munc13–1 Homodimer to Munc13–1/RIM Heterodimer Switch

Lu, J., Machius, M., Dulubova, I., Dai, H., Südhof, T. C., Tomchick, D. R., & Rizo, J. (2006) · PLoS Biology

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 132

Crystal Structure of the Tp34 (TP0971) Lipoprotein of Treponema pallidum

Deka, R. K., Brautigam, C. A., Tomson, F. L., Lumpkins, S. B., Tomchick, D. R., Machius, M., & Norgard, M. V. (2007) · Journal of Biological Chemistry

Syphilis Diagnosis and TreatmentEnzyme Structure and Function

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