Wrana, Jeffrey L.

Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration

Luga, V., Zhang, L., Viloria-Petit, A. M., Ogunjimi, A. A., Inanlou, M. R., Chiu, E., Buchanan, M., Hosein, A. N., Basik, M., & Wrana, J. L. (2012) · Cell

Extracellular vesicles in diseaseCancer Cells and Metastasis

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Regulation of the Polarity Protein Par6 by TGFß Receptors Controls Epithelial Cell Plasticity

Ozdamar, B., Bose, R., Barrios-Rodiles, M., Wang, H.-R., Zhang, Y., & Wrana, J. L. (2005) · Science

TGF-β signaling in diseasesCancer Cells and Metastasis

Cited by 881

Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients

Isho, B., Abe, K. T., Zuo, M., Jamal, A. J., Rathod, B., Wang, J. H., Li, Z., Chao, G., Rojas, O. L., Bang, Y. M., et al. (2020) · Science Immunology

SARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testing

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Regulation of Cytokine Receptors by Golgi N-Glycan Processing and Endocytosis

Partridge, E. A., Le Roy, C., Di Guglielmo, G. M., Pawling, J., Cheung, P., Granovsky, M., Nabi, I. R., Wrana, J. L., & Dennis, J. W. (2004) · Science

Glycosylation and Glycoproteins ResearchGalectins and Cancer Biology

Cited by 735

A Highly Conserved Program of Neuronal Microexons Is Misregulated in Autistic Brains

Irimia, M., Weatheritt, R. J., Ellis, J. D., Parikshak, N. N., Gonatopoulos-Pournatzis, T., Babor, M., Quesnel-Vallières, M., Tapial, J., Raj, B., O’Hanlon, D., et al. (2014) · Cell

RNA Research and SplicingRNA regulation and disease

Cited by 693

Independent Regulation of Collagenase, 72-kDa Progelatinase, and Metalloendoproteinase Inhibitor Expression in Human Fibroblasts by Transforming Growth Factor-β

Overall, C. M., Wrana, J. L., & Sodek, J. (1989) · Journal of Biological Chemistry

Protease and Inhibitor MechanismsTGF-β signaling in diseases

Cited by 636

Regulation of cell polarity and protrusion formation by targeting RhoA for degradation

Wang, H.-R., Zhang, Y., Ozdamar, B., Ogunjimi, A. A., Alexandrova, E., Thomsen, G. H., & Wrana, J. L. (2003) · Science

Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions

Cited by 551

Tissue-specific alternative splicing remodels protein-protein interaction networks

Ellis, J. D., Barrios-Rodiles, M., Çolak, R., Irimia, M., Kim, T., Calarco, J. A., Wang, X., Pan, Q., O'Hanlon, D., Kim, P. M., et al. (2012) · Molecular Cell

RNA Research and SplicingCancer-related molecular mechanisms research

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Activation of Signalling by the Activin Receptor Complex

Attisano, L., Wrana, J. L., Montalvo, E., & Massagué, J. (1996) · Molecular and Cellular Biology

TGF-β signaling in diseasesProtein Kinase Regulation and GTPase Signaling

Cited by 316

ProHits: integrated software for mass spectrometry–based interaction proteomics

Liu, G., Zhang, J., Larsen, B., Stark, C., Breitkreutz, A., Lin, Z.-Y., Breitkreutz, B.-J., Ding, Y., Colwill, K., Pasculescu, A., et al. (2010) · Nature Biotechnology

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 243

FoxH1(Fast) functions to specify the anterior primitive streak in the mouse

Hoodless, P. A., Pye, M., Chazaud, C., Labbé, E., Attisano, L., Rossant, J., & Wrana, J. L. (2001) · Genes & Development

Developmental Biology and Gene RegulationPluripotent Stem Cells Research

Cited by 203

Disulfiram when Combined with Copper Enhances the Therapeutic Effects of Temozolomide for the Treatment of Glioblastoma

Lun, X., Wells, J. C., Grinshtein, N., King, J. C., Hao, X., Dang, N.-H., Wang, X., Aman, A., Uehling, D., Datti, A., et al. (2016) · Clinical Cancer Research

Glioma Diagnosis and TreatmentCancer Cells and Metastasis

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TCF1 links GIPR signaling to the control of beta cell function and survival

Campbell, J. E., Ussher, J. R., Mulvihill, E. E., Kolic, J., Baggio, L. L., Cao, X., Liu, Y., Lamont, B. J., Morii, T., Streutker, C. J., et al. (2016) · Nature Medicine

Pancreatic function and diabetesDiabetes Treatment and Management

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Turning it up a Notch: cross-talk between TGFβ and Notch signaling: What the papers say

Klüppel, M., & Wrana, J. L. (2005) · BioEssays

Developmental Biology and Gene RegulationTGF-β signaling in diseases

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Myofibroblast YAP/TAZ activation is a key step in organ fibrogenesis

He, X., Tolosa, M. F., Zhang, T., Goru, S. K., Ulloa Severino, L., Misra, P. S., McEvoy, C. M., Caldwell, L., Szeto, S. G., Gao, F., et al. (2022) · JCI Insight

Hippo pathway signaling and YAP/TAZLiver physiology and pathology

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Inhibition of the Sodium Potassium Adenosine Triphosphatase Pump Sensitizes Cancer Cells to Anoikis and Prevents Distant Tumor Formation

Simpson, C. D., Mawji, I. A., Anyiwe, K., Williams, M. A., Wang, X., Venugopal, A. L., Gronda, M., Hurren, R., Cheng, S., Serra, S., et al. (2009) · Cancer Research

Cell death mechanisms and regulationIon Transport and Channel Regulation

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A feed forward loop enforces YAP/TAZ signaling during tumorigenesis

Gill, M. K., Christova, T., Zhang, Y. Y., Gregorieff, A., Zhang, L., Narimatsu, M., Song, S., Xiong, S., Couzens, A. L., Tong, J., et al. (2018) · Nature Communications

Hippo pathway signaling and YAP/TAZCancer-related molecular mechanisms research

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The hippo pathway: A master regulator of liver metabolism, regeneration, and disease

Nguyen‐Lefebvre, A. T., Selzner, N., Wrana, J. L., & Bhat, M. (2021) · The FASEB Journal

Hippo pathway signaling and YAP/TAZLiver physiology and pathology

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Chromatin remodelling in damaged intestinal crypts orchestrates redundant TGFβ and Hippo signalling to drive regeneration

Fink, M., Njah, K., Patel, S. J., Cook, D. P., Man, V., Ruso, F., Rajan, A., Narimatsu, M., Obersterescu, A., Pye, M. J., et al. (2024) · Nature Cell Biology

Hippo pathway signaling and YAP/TAZDigestive system and related health

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Crucial Role of Postsynaptic Syntaxin 4 in Mediating Basal Neurotransmission and Synaptic Plasticity in Hippocampal CA1 Neurons

Bin, N.-R., Ma, K., Harada, H., Tien, C.-W., Bergin, F., Sugita, K., Luyben, T. T., Narimatsu, M., Jia, Z., Wrana, J. L., et al. (2018) · Cell Reports

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

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