Haley, Benjamin

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

Kayagaki, N., Stowe, I. B., Lee, B. L., O’Rourke, K., Anderson, K., Warming, S., Cuellar, T., Haley, B., Roose-Girma, M., Phung, Q. T., et al. (2015) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

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Kinetic analysis of the RNAi enzyme complex

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RNA Interference and Gene DeliveryRNA Research and Splicing

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IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines

Tahtinen, S., Tong, A.-J., Himmels, P., Oh, J., Paler-Martinez, A., Kim, L., Wichner, S., Oei, Y., McCarron, M. J., Freund, E. C., et al. (2022) · Nature Immunology

Immune Response and InflammationImmunotherapy and Immune Responses

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Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure

Guler, G. D., Tindell, C. A., Pitti, R., Wilson, C., Nichols, K., KaiWai Cheung, T., Kim, H.-J., Wongchenko, M., Yan, Y., Haley, B., et al. (2017) · Cancer Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

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KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer

Burgess, M. R., Hwang, E., Mroue, R., Bielski, C. M., Wandler, A. M., Huang, B. J., Firestone, A. J., Young, A., Lacap, J. A., Crocker, L., et al. (2017) · Cell

Melanoma and MAPK PathwaysCancer Genomics and Diagnostics

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Disruption of IRE1α through its kinase domain attenuates multiple myeloma

Harnoss, J. M., Le Thomas, A., Shemorry, A., Marsters, S. A., Lawrence, D. A., Lu, M., Chen, Y.-C. A., Qing, J., Totpal, K., Kan, D., et al. (2019) · Proceedings of the National Academy of Sciences

Endoplasmic Reticulum Stress and DiseaseMultiple Myeloma Research and Treatments

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Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex

Kolumam, G., Chen, M. Z., Tong, R., Zavala-Solorio, J., Kates, L., van Bruggen, N., Ross, J., Wyatt, S. K., Gandham, V. D., Carano, R. A. D., et al. (2015) · EBioMedicine

Fibroblast Growth Factor ResearchAdipose Tissue and Metabolism

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High-efficiency nonviral CRISPR/Cas9-mediated gene editing of human T cells using plasmid donor DNA

Oh, S. A., Senger, K., Madireddi, S., Akhmetzyanova, I., Ishizuka, I. E., Tarighat, S., Lo, J. H., Shaw, D., Haley, B., & Rutz, S. (2022) · Journal of Experimental Medicine

CRISPR and Genetic EngineeringCAR-T cell therapy research

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TEAD Proteins Associate With DNA Repair Proteins to Facilitate Cellular Recovery From DNA Damage

Calses, P. C., Pham, V. C., Guarnaccia, A. D., Choi, M., Verschueren, E., Bakker, S. T., Pham, T. H., Hinkle, T., Liu, C., Chang, M. T., et al. (2023) · Molecular & Cellular Proteomics

Hippo pathway signaling and YAP/TAZDNA Repair Mechanisms

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