Irvine, Katharine M.

Histone deacetylases as regulators of inflammation and immunity

Shakespear, M. R., Halili, M. A., Irvine, K. M., Fairlie, D. P., & Sweet, M. J. (2011) · Trends in Immunology

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 546

The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease

Gadd, V. L., Skoien, R., Powell, E. E., Fagan, K. J., Winterford, C., Horsfall, L., Irvine, K., & Clouston, A. D. (2014) · Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 452

Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS

Halili, M. A., Andrews, M. R., Labzin, L. I., Schroder, K., Matthias, G., Cao, C., Lovelace, E., Reid, R. C., Le, G. T., Hume, D. A., et al. (2010) · Journal of Leukocyte Biology

Histone Deacetylase Inhibitors ResearchImmune Response and Inflammation

Cited by 186

A Transgenic Line That Reports CSF1R Protein Expression Provides a Definitive Marker for the Mouse Mononuclear Phagocyte System

Grabert, K., Sehgal, A., Irvine, K. M., Wollscheid-Lengeling, E., Ozdemir, D. D., Stables, J., Luke, G. A., Ryan, M. D., Adamson, A., Humphreys, N. E., et al. (2020) · The Journal of Immunology

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 114

Can paracetamol (acetaminophen) be administered to patients with liver impairment?

Hayward, K. L., Powell, E. E., Irvine, K. M., & Martin, J. H. (2016) · British Journal of Clinical Pharmacology

Drug-Induced Hepatotoxicity and ProtectionLiver Disease and Transplantation

Cited by 104

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration

Irvine, K. M., Skoien, R., Bokil, N. J., Melino, M., Thomas, G. P., Loo, D., Gabrielli, B., Hill, M. M., Sweet, M. J., Clouston, A. D., et al. (2014) · World Journal of Gastroenterology

Telomeres, Telomerase, and SenescenceLiver physiology and pathology

Cited by 97

Salmonella employs multiple mechanisms to subvert the TLR‐inducible zinc‐mediated antimicrobial response of human macrophages

Kapetanovic, R., Bokil, N. J., Achard, M. E. S., Ong, C. Y., Peters, K. M., Stocks, C. J., Phan, M., Monteleone, M., Schroder, K., Irvine, K. M., et al. (2016) · The FASEB Journal

Immune Response and InflammationSalmonella and Campylobacter epidemiology

Cited by 86

ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosis

Nalkurthi, C., Schroder, W. A., Melino, M., Irvine, K. M., Nyuydzefe, M., Chen, W., Liu, J., Teng, M. W. L., Hill, G. R., Bertolino, P., et al. (2022) · JHEP Reports

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 75

The combination of gene perturbation assay and ChIP-chip reveals functional direct target genes for IRF8 in THP-1 cells

Kubosaki, A., Lindgren, G., Tagami, M., Simon, C., Tomaru, Y., Miura, H., Suzuki, T., Arner, E., Forrest, A. R. R., Irvine, K. M., et al. (2010) · Molecular Immunology

interferon and immune responsesGenomics and Chromatin Dynamics

Cited by 29