A Transgenic Line That Reports CSF1R Protein Expression Provides a Definitive Marker for the Mouse Mononuclear Phagocyte System

Grabert, Kathleen; Sehgal, Anuj; Irvine, Katharine M; Wollscheid-Lengeling, Evi; Ozdemir, Derya D; Stables, Jennifer; Luke, Garry A; Ryan, Martin D; Adamson, Antony; Humphreys, Neil E; Sandrock, Cheyenne J; Rojo, Rocio; Verkasalo, Veera A; Mueller, Werner; Hohenstein, Peter; Pettit, Allison R; Pridans, Clare; Hume, David A

doi:10.4049/jimmunol.2000835

A Transgenic Line That Reports CSF1R Protein Expression Provides a Definitive Marker for the Mouse Mononuclear Phagocyte System

The proliferation, differentiation, and survival of cells of the mononuclear phagocyte system (MPS; progenitors, monocytes, macrophages, and classical dendritic cells) are controlled by signals from the M-CSF receptor (CSF1R). Cells of the MPS lineage have been identified using numerous surface m…