Thomas, David M.

Translational biology of osteosarcoma

Kansara, M., Teng, M. W., Smyth, M. J., & Thomas, D. M. (2014) · Nature Reviews Cancer

Sarcoma Diagnosis and TreatmentBone Tumor Diagnosis and Treatments

Cited by 1,294

The Retinoblastoma Protein Acts as a Transcriptional Coactivator Required for Osteogenic Differentiation

Thomas, D. M., Carty, S. A., Piscopo, D. M., Lee, J.-S., Wang, W.-F., Forrester, W. C., & Hinds, P. W. (2001) · Molecular Cell

Bone Metabolism and DiseasesSarcoma Diagnosis and Treatment

Cited by 361

Clinical Overview of MDM2/X-Targeted Therapies

Burgess, A., Chia, K. M., Haupt, S., Thomas, D., Haupt, Y., & Lim, E. (2016) · Frontiers in Oncology

Cancer-related Molecular PathwaysPI3K/AKT/mTOR signaling in cancer

Cited by 315

Frequency of Pathogenic Germline Variants in Cancer-Susceptibility Genes in Patients With Osteosarcoma

Mirabello, L., Zhu, B., Koster, R., Karlins, E., Dean, M., Yeager, M., Gianferante, M., Spector, L. G., Morton, L. M., Karyadi, D., et al. (2020) · JAMA Oncology

Sarcoma Diagnosis and TreatmentBRCA gene mutations in cancer

Cited by 243

The Architecture and Evolution of Cancer Neochromosomes

Garsed, D. W., Marshall, O. J., Corbin, V. D. A., Hsu, A., Di Stefano, L., Schröder, J., Li, J., Feng, Z.-P., Kim, B. W., Kowarsky, M., et al. (2014) · Cancer Cell

Genomic variations and chromosomal abnormalitiesSarcoma Diagnosis and Treatment

Cited by 194

RECK—a newly discovered inhibitor of metastasis with prognostic significance in multiple forms of cancer

Clark, J. C. M., Thomas, D. M., Choong, P. F. M., & Dass, C. R. (2007) · Cancer and Metastasis Reviews

Protease and Inhibitor MechanismsMechanisms of cancer metastasis

Cited by 176

Comprehensive Mapping of p53 Pathway Alterations Reveals an Apparent Role for Both SNP309 and MDM2 Amplification in Sarcomagenesis

Ito, M., Barys, L., O'Reilly, T., Young, S., Gorbatcheva, B., Monahan, J., Zumstein-Mecker, S., Choong, P. F., Dickinson, I., Crowe, P., et al. (2011) · Clinical Cancer Research

Cancer-related Molecular PathwaysSarcoma Diagnosis and Treatment

Cited by 115

MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer

Cipponi, A., Goode, D. L., Bedo, J., McCabe, M. J., Pajic, M., Croucher, D. R., Rajal, A. G., Junankar, S. R., Saunders, D. N., Lobachevsky, P., et al. (2020) · Science

PI3K/AKT/mTOR signaling in cancerEvolution and Genetic Dynamics

Cited by 103

Role of the Retinoblastoma Protein in Differentiation and Senescence

Thomas, D. M., Yang, H.-S., Alexander, K., & Hinds, P. W. (2003) · Cancer Biology & Therapy

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 100

The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly

Pinese, M., Lacaze, P., Rath, E. M., Stone, A., Brion, M.-J., Ameur, A., Nagpal, S., Puttick, C., Husson, S., Degrave, D., et al. (2020) · Nature Communications

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 70

Management of sarcoma in the Asia-Pacific region: resource-stratified guidelines.

Lewin, J., Puri, A., Quek, R., Ngan, R., Alcasabas, A. P., Wood, D., & Thomas, D. (2013) · The Lancet Oncology

Sarcoma Diagnosis and TreatmentBone Tumor Diagnosis and Treatments

Cited by 44