Faccio, Roberta

TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy

Molgora, M., Esaulova, E., Vermi, W., Hou, J., Chen, Y., Luo, J., Brioschi, S., Bugatti, M., Omodei, A. S., Ricci, B., et al. (2020) · Cell

Cancer Immunotherapy and BiomarkersImmune cells in cancer

Cited by 656

Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis

Ruhland, M. K., Loza, A. J., Capietto, A.-H., Luo, X., Knolhoff, B. L., Flanagan, K. C., Belt, B. A., Alspach, E., Leahy, K., Luo, J., et al. (2016) · Nature Communications

Telomeres, Telomerase, and SenescenceImmune cells in cancer

Cited by 496

PLCγ2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB2

Mao, D., Epple, H., Uthgenannt, B., Novack, D. V., & Faccio, R. (2006) · Journal of Clinical Investigation

Bone Metabolism and DiseasesRheumatoid Arthritis Research and Therapies

Cited by 214

Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development

Luo, X., Fu, Y., Loza, A. J., Murali, B., Leahy, K. M., Ruhland, M. K., Gang, M., Su, X., Zamani, A., Shi, Y., et al. (2016) · Cell Reports

Bone health and treatmentsTelomeres, Telomerase, and Senescence

Cited by 141

Therapy-Induced Senescence Drives Bone Loss

Yao, Z., Murali, B., Ren, Q., Luo, X., Faget, D. V., Cole, T., Ricci, B., Thotala, D., Monahan, J., van Deursen, J. M., et al. (2020) · Cancer Research

Telomeres, Telomerase, and SenescenceBone health and treatments

Cited by 129

Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCγ2 signaling axis in mice

Graham, D. B., Robertson, C. M., Bautista, J., Mascarenhas, F., Diacovo, M. J., Montgrain, V., Lam, S. K., Cremasco, V., Dunne, W. M., Faccio, R., et al. (2007) · Journal of Clinical Investigation

Neutrophil, Myeloperoxidase and Oxidative MechanismsRedox biology and oxidative stress

Cited by 124

Activation of αvβ3Integrin on Human Osteoclast-like Cells Stimulates Adhesion and Migration in Response to Osteopontin

Faccio, R., Grano, M., Colucci, S., Zallone, A. Z., Quaranta, V., & Pelletier, A. J. (1998) · Biochemical and Biophysical Research Communications

Cell Adhesion Molecules ResearchBone Metabolism and Diseases

Cited by 64

Vav/Phospholipase Cγ2–mediated control of a neutrophil‐dependent murine model of rheumatoid arthritis

Cremasco, V., Graham, D. B., Novack, D. V., Swat, W., & Faccio, R. (2008) · Arthritis & Rheumatism

Rheumatoid Arthritis Research and TherapiesCell Adhesion Molecules Research

Cited by 51

Antagonism of Inhibitor of Apoptosis Proteins Increases Bone Metastasis via Unexpected Osteoclast Activation

Yang, C., Davis, J. L., Zeng, R., Vora, P., Su, X., Collins, L. I., Vangveravong, S., Mach, R. H., Piwnica-Worms, D., Weilbaecher, K. N., et al. (2013) · Cancer Discovery

Bone Metabolism and DiseasesBone health and treatments

Cited by 50

The retinoblastoma tumor suppressor is a critical intrinsic regulator for hematopoietic stem and progenitor cells under stress

Daria, D., Filippi, M.-D., Knudsen, E. S., Faccio, R., Li, Z., Kalfa, T., & Geiger, H. (2008) · Blood

Hematopoietic Stem Cell TransplantationBlood disorders and treatments

Cited by 46