Veit, Guido

Mechanism-based corrector combination restores ΔF508-CFTR folding and function

Okiyoneda, T., Veit, G., Dekkers, J. F., Bagdany, M., Soya, N., Xu, H., Roldan, A., Verkman, A. S., Kurth, M., Simon, A., et al. (2013) · Nature Chemical Biology

Cystic Fibrosis Research AdvancesIon Transport and Channel Regulation

Cited by 378

Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression

Veit, G., Avramescu, R. G., Perdomo, D., Phuan, P.-W., Bagdany, M., Apaja, P. M., Borot, F., Szollosi, D., Wu, Y.-S., Finkbeiner, W. E., et al. (2014) · Science Translational Medicine

Cystic Fibrosis Research AdvancesIon Transport and Channel Regulation

Cited by 287

Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination

Veit, G., Roldan, A., Hancock, M. A., Da Fonte, D. F., Xu, H., Hussein, M., Frenkiel, S., Matouk, E., Velkov, T., & Lukacs, G. L. (2020) · JCI Insight

Cystic Fibrosis Research AdvancesIon Transport and Channel Regulation

Cited by 250

Recessive and dominant mutations in COL12A1 cause a novel EDS/myopathy overlap syndrome in humans and mice

Zou, Y., Zwolanek, D., Izu, Y., Gandhy, S., Schreiber, G., Brockmann, K., Devoto, M., Tian, Z., Hu, Y., Veit, G., et al. (2014) · Human Molecular Genetics

Muscle Physiology and DisordersConnective tissue disorders research

Cited by 143

Structure-guided combination therapy to potently improve the function of mutant CFTRs

Veit, G., Xu, H., Dreano, E., Avramescu, R. G., Bagdany, M., Beitel, L. K., Roldan, A., Hancock, M. A., Lay, C., Li, W., et al. (2018) · Nature Medicine

Cystic Fibrosis Research AdvancesGenetic and Kidney Cyst Diseases

Cited by 134

Mutation-specific downregulation of CFTR2 variants by gating potentiators

Avramescu, R. G., Kai, Y., Xu, H., Bidaud-Meynard, A., Schnúr, A., Frenkiel, S., Matouk, E., Veit, G., & Lukacs, G. L. (2017) · Human Molecular Genetics

Cystic Fibrosis Research AdvancesInhalation and Respiratory Drug Delivery

Cited by 43

Analysis of obstetric complications and uterine connective tissue in tenascin-X-deficient humans and mice

Egging, D. F., van Vlijmen-Willems, I., Choi, J., Peeters, A. C. T. M., van Rens, D., Veit, G., Koch, M., Davis, E. C., & Schalkwijk, J. (2008) · Cell and Tissue Research

Connective tissue disorders researchPregnancy-related medical research

Cited by 27