Zavacki, Ann Marie

Bile Acids: Natural Ligands for an Orphan Nuclear Receptor

Parks, D. J., Blanchard, S. G., Bledsoe, R. K., Chandra, G., Consler, T. G., Kliewer, S. A., Stimmel, J. B., Willson, T. M., Zavacki, A. M., Moore, D. D., et al. (1999) · Science

Cholesterol and Lipid MetabolismDrug Transport and Resistance Mechanisms

Cited by 2,274

Defects in Adaptive Energy Metabolism with CNS-Linked Hyperactivity in PGC-1α Null Mice

Lin, J., Wu, P.-H., Tarr, P. T., Lindenberg, K. S., St-Pierre, J., Zhang, C.-Y., Mootha, V. K., Jäger, S., Vianna, C. R., Reznick, R. M., et al. (2004) · Cell

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 1,162

Cellular and Molecular Basis of Deiodinase-Regulated Thyroid Hormone Signaling1

Gereben, B., Zavacki, A. M., Ribich, S., Kim, B. W., Huang, S. A., Simonides, W. S., Zeöld, A., & Bianco, A. C. (2008) · Endocrine Reviews

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 891

The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate

Dentice, M., Bandyopadhyay, A., Gereben, B., Callebaut, I., Christoffolete, M. A., Kim, B. W., Nissim, S., Mornon, J.-P., Zavacki, A. M., Zeöld, A., et al. (2005) · Nature Cell Biology

Hedgehog Signaling Pathway StudiesUbiquitin and proteasome pathways

Cited by 227

Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells

Freitas, B. C. G., Gereben, B., Castillo, M., Kalló, I., Zeöld, A., Egri, P., Liposits, Z., Zavacki, A. M., Maciel, R. M. B., Jo, S., et al. (2010) · Journal of Clinical Investigation

Thyroid Disorders and TreatmentsEstrogen and related hormone effects

Cited by 160

A novel retinoid X receptor-independent thyroid hormone response element is present in the human type 1 deiodinase gene

Toyoda, N., Zavacki, A. M., Maia, A. L., Harney, J. W., & Larsen, P. R. (1995) · Molecular and Cellular Biology

Thyroid Disorders and TreatmentsEstrogen and related hormone effects

Cited by 142

Type 1 iodothyronine deiodinase is a sensitive marker of peripheral thyroid status in the mouse

Zavacki, A. M., Ying, H., Christoffolete, M. A., Aerts, G., So, E., Harney, J. W., Cheng, S.-Y., Larsen, P. R., & Bianco, A. C. (2005) · Endocrinology

Thyroid Disorders and TreatmentsEstrogen and related hormone effects

Cited by 138

Ubiquitination-induced conformational change within the deiodinase dimer is a switch regulating enzyme activity

Sagar, G. D. V., Gereben, B., Callebaut, I., Mornon, J.-P., Zeöld, A., da Silva, W. S., Luongo, C., Dentice, M., Tente, S. M., Freitas, B. C. G., et al. (2007) · Molecular and Cellular Biology

Ubiquitin and proteasome pathwaysThyroid Disorders and Treatments

Cited by 103

Mice with Impaired Extrathyroidal Thyroxine to 3,5,3′-Triiodothyronine Conversion Maintain Normal Serum 3,5,3′-Triiodothyronine Concentrations

Christoffolete, M. A., Arrojo e Drigo, R., Gazoni, F., Tente, S. M., Goncalves, V., Amorim, B. S., Larsen, P. R., Bianco, A. C., & Zavacki, A. M. (2007) · Endocrinology

Thyroid Disorders and TreatmentsGrowth Hormone and Insulin-like Growth Factors

Cited by 62

A novel pathway regulates thyroid hormone availability in rat and human hypothalamic neurosecretory neurons

Kalló, I., Mohácsik, P., Vida, B., Zeöld, A., Bardóczi, Z., Zavacki, A. M., Farkas, E., Kádár, A., Hrabovszky, E., Arrojo e Drigo, R., et al. (2012) · PLoS ONE

Thyroid Disorders and TreatmentsHypothalamic control of reproductive hormones

Cited by 52

Thyroxine-induced expression of pyroglutamyl peptidase II and inhibition of TSH release precedes suppression of TRH mRNA and requires type 2 deiodinase

Marsili, A., Sanchez, E., Singru, P., Harney, J. W., Zavacki, A. M., Lechan, R. M., & Larsen, P. R. (2011) · Journal of Endocrinology

Thyroid Disorders and TreatmentsNeuropeptides and Animal Physiology

Cited by 27