Adorini, Luciano

Efficacy and safety of the farnesoid X receptor agonist obeticholic acid in patients with type 2 diabetes and nonalcoholic fatty liver disease

Mudaliar, S., Henry, R. R., Sanyal, A. J., Morrow, L., Marschall, H., Kipnes, M., Adorini, L., Sciacca, C. I., Clopton, P., Castelloe, E., et al. (2013) · Gastroenterology

Liver Disease Diagnosis and TreatmentDrug Transport and Resistance Mechanisms

Cited by 931

Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

Gadaleta, R. M., van Erpecum, K. J., Oldenburg, B., Willemsen, E. C. L., Renooij, W., Murzilli, S., Klomp, L. W. J., Siersema, P. D., Schipper, M. E. I., Danese, S., et al. (2011) · Gut

Inflammatory Bowel DiseaseGut microbiota and health

Cited by 870

Microbiota-driven gut vascular barrier disruption is a prerequisite for non-alcoholic steatohepatitis development

Mouries, J., Brescia, P., Silvestri, A., Spadoni, I., Sorribas, M., Wiest, R., Mileti, E., Galbiati, M., Invernizzi, P., Adorini, L., et al. (2019) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentGut microbiota and health

Cited by 688

Efficacy of obeticholic acid in patients with primary biliary cirrhosis and inadequate response to ursodeoxycholic acid

Hirschfield, G. M., Mason, A., Luketic, V., Lindor, K., Gordon, S. C., Mayo, M., Kowdley, K. V., Vincent, C., Bodhenheimer, H. C., Parés, A., et al. (2015) · Gastroenterology

Liver Diseases and ImmunityDrug Transport and Resistance Mechanisms

Cited by 576

A randomized trial of obeticholic acid monotherapy in patients with primary biliary cholangitis

Kowdley, K. V., Luketic, V., Chapman, R., Hirschfield, G. M., Poupon, R., Schramm, C., Vincent, C., Rust, C., Parés, A., Mason, A., et al. (2018) · Hepatology

Liver Diseases and ImmunityDrug Transport and Resistance Mechanisms

Cited by 281

Farnesoid X receptor targeting to treat nonalcoholic steatohepatitis

Adorini, L., Pruzanski, M., & Shapiro, D. (2012) · Drug Discovery Today

Liver Disease Diagnosis and TreatmentDrug Transport and Resistance Mechanisms

Cited by 259

Bile Acid Receptor Activation Modulates Hepatic Monocyte Activity and Improves Nonalcoholic Fatty Liver Disease

McMahan, R. H., Wang, X. X., Cheng, L. L., Krisko, T., Smith, M., El Kasmi, K., Pruzanski, M., Adorini, L., Golden-Mason, L., Levi, M., et al. (2013) · Journal of Biological Chemistry

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 225

Farnesoid X receptor activation increases reverse cholesterol transport by modulating bile acid composition and cholesterol absorption in mice

Xu, Y., Li, F., Zalzala, M., Xu, J., Gonzalez, F. J., Adorini, L., Lee, Y., Yin, L., & Zhang, Y. (2016) · Hepatology

Cholesterol and Lipid MetabolismDrug Transport and Resistance Mechanisms

Cited by 172

FXR-dependent modulation of the human small intestinal microbiome by the bile acid derivative obeticholic acid

Friedman, E. S., Li, Y., Shen, T.-C. D., Jiang, J., Chau, L., Adorini, L., Babakhani, F., Edwards, J., Shapiro, D., Zhao, C., et al. (2018) · Gastroenterology

Gut microbiota and healthDrug Transport and Resistance Mechanisms

Cited by 149

Inflammation in multiple sclerosis: the good, the bad, and the complex

Martino, G., Adorini, L., Rieckmann, P., Hillert, J., Kallmann, B., Comi, G., & Filippi, M. (2002) · The Lancet Neurology

Multiple Sclerosis Research StudiesPsoriasis: Treatment and Pathogenesis

Cited by 142

Metabolic syndrome induces inflammation and impairs gonadotropin-releasing hormone neurons in the preoptic area of the hypothalamus in rabbits

Morelli, A., Sarchielli, E., Comeglio, P., Filippi, S., Vignozzi, L., Marini, M., Rastrelli, G., Maneschi, E., Cellai, I., Persani, L., et al. (2014) · Molecular and Cellular Endocrinology

Hypothalamic control of reproductive hormonesRegulation of Appetite and Obesity

Cited by 107

Vitamin D Endocrine System and the Immune Response in Rheumatic Diseases

Cutolo, M., Plebani, M., Shoenfeld, Y., Adorini, L., & Tincani, A. (2011) · Vitamins & Hormones

Vitamin D Research StudiesSystemic Lupus Erythematosus Research

Cited by 86

Obeticholic acid and INT-767 modulate collagen deposition in a NASH in vitro model

Anfuso, B., Tiribelli, C., Adorini, L., & Rosso, N. (2020) · Scientific Reports

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 43