Zaitlen, Noah

Variance component model to account for sample structure in genome-wide association studies

Kang, H. M., Sul, J. H., Service, S. K., Zaitlen, N. A., Kong, S.-Y., Freimer, N. B., Sabatti, C., & Eskin, E. (2010) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,817

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Vilhjálmsson, B. J., Yang, J., Finucane, H. K., Gusev, A., Lindström, S., Ripke, S., Genovese, G., Loh, P.-R., Bhatia, G., Do, R., et al. (2015) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,303

Multiplexed droplet single-cell RNA-sequencing using natural genetic variation

Kang, H. M., Subramaniam, M., Targ, S., Nguyen, M., Maliskova, L., McCarthy, E., Wan, E., Wong, S., Byrnes, L., Lanata, C. M., et al. (2018) · Nature Biotechnology

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 1,101

Advantages and pitfalls in the application of mixed-model association methods

Yang, J., Zaitlen, N. A., Goddard, M. E., Visscher, P. M., & Price, A. L. (2014) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 981

Genome-wide association study of bipolar disorder in European American and African American individuals

Smith, E. N., Bloss, C. S., Badner, J. A., Barrett, T., Belmonte, P. L., Berrettini, W., Byerley, W., Coryell, W., Craig, D., Edenberg, H. J., et al. (2009) · Molecular Psychiatry

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 363

Transethnic Genetic-Correlation Estimates from Summary Statistics

Brown, B. C., Ye, C. J., Price, A. L., & Zaitlen, N. (2016) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 340

Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia

Tam, O. H., Rozhkov, N. V., Shaw, R., Kim, D., Hubbard, I., Fennessey, S., Propp, N., Phatnani, H., Kwan, J., Sareen, D., et al. (2019) · Cell Reports

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 327

Extremely low-coverage sequencing and imputation increases power for genome-wide association studies

Pasaniuc, B., Rohland, N., McLaren, P. J., Garimella, K., Zaitlen, N., Li, H., Gupta, N., Neale, B. M., Daly, M. J., Sklar, P., et al. (2012) · Nature Genetics

Genetic Associations and EpidemiologyGenomics and Phylogenetic Studies

Cited by 299

Intersection of population variation and autoimmunity genetics in human T cell activation

Ye, C. J., Feng, T., Kwon, H.-K., Raj, T., Wilson, M. T., Asinovski, N., McCabe, C., Lee, M. H., Frohlich, I., Paik, H.-I., et al. (2014) · Science

T-cell and B-cell ImmunologyGenetic Associations and Epidemiology

Cited by 236

Massively parallel functional annotation of 3′ untranslated regions

Zhao, W., Pollack, J. L., Blagev, D. P., Zaitlen, N., McManus, M. T., & Erle, D. J. (2014) · Nature Biotechnology

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 125

Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes in response to immune checkpoint inhibitors

Nassar, A. H., Adib, E., Abou Alaiwi, S., El Zarif, T., Groha, S., Akl, E. W., Nuzzo, P. V., Mouhieddine, T. H., Perea-Chamblee, T., Taraszka, K., et al. (2022) · Cancer Cell

Cancer Immunotherapy and BiomarkersCancer Genomics and Diagnostics

Cited by 121

Estimating cross‐population genetic correlations of causal effect sizes

Galinsky, K. J., Reshef, Y. A., Finucane, H. K., Loh, P., Zaitlen, N., Patterson, N. J., Brown, B. C., & Price, A. L. (2019) · Genetic Epidemiology

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 75

Leveraging population admixture to characterize the heritability of complex traits

Zaitlen, N., Pasaniuc, B., Sankararaman, S., Bhatia, G., Zhang, J., Gusev, A., Young, T., Tandon, A., Pollack, S., Vilhjálmsson, B. J., et al. (2014) · Nature Genetics

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 63

Comparing Ethnicity-Specific Reference Intervals for Clinical Laboratory Tests from EHR Data

Rappoport, N., Paik, H., Oskotsky, B., Tor, R., Ziv, E., Zaitlen, N., & Butte, A. J. (2018) · The Journal of Applied Laboratory Medicine

Clinical Laboratory Practices and Quality ControlRace, Genetics, and Society

Cited by 49

Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits

Zaitlen, N., Kraft, P., Patterson, N., Pasaniuc, B., Bhatia, G., Pollack, S., & Price, A. L. (2013) · PLoS Genetics

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 32

Singleton Variants Dominate the Genetic Architecture of Human Gene Expression

Hernandez, R. D., Uricchio, L. H., Hartman, K., Ye, C., Dahl, A., & Zaitlen, N. (2018) · SSRN Electronic Journal

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 6