Sampson, Timothy R.

Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson's disease

Sampson, T. R., Debelius, J. W., Thron, T., Janssen, S., Shastri, G. G., Ilhan, Z. E., Challis, C., Schretter, C. E., Rocha, S., Gradinaru, V., et al. (2016) · Cell

Parkinson's Disease Mechanisms and TreatmentsGut microbiota and health

Cited by 3,622

The central nervous system and the gut microbiome

Sharon, G., Sampson, T. R., Geschwind, D. H., & Mazmanian, S. K. (2016) · Cell

Gut microbiota and healthNeurogenesis and neuroplasticity mechanisms

Cited by 1,513

Control of brain development, function, and behavior by the microbiome

Sampson, T. R., & Mazmanian, S. K. (2015) · Cell Host & Microbe

Gut microbiota and healthTryptophan and brain disorders

Cited by 1,093

Gut microbiota regulate Alzheimer’s disease pathologies and cognitive disorders via PUFA-associated neuroinflammation

Chen, C., Liao, J., Xia, Y., Liu, X., Jones, R., Haran, J., McCormick, B., Sampson, T. R., Alam, A., & Ye, K. (2022) · Gut

Gut microbiota and healthAlzheimer's disease research and treatments

Cited by 491

A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice

Sampson, T. R., Challis, C., Jain, N., Moiseyenko, A., Ladinsky, M. S., Shastri, G. G., Thron, T., Needham, B. D., Horvath, I., Debelius, J. W., et al. (2020) · eLife

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 439

Gut-seeded α-synuclein fibrils promote gut dysfunction and brain pathology specifically in aged mice

Challis, C., Hori, A., Sampson, T. R., Yoo, B. B., Challis, R. C., Hamilton, A. M., Mazmanian, S. K., Volpicelli-Daley, L. A., & Gradinaru, V. (2020) · Nature Neuroscience

Parkinson's Disease Mechanisms and TreatmentsLysosomal Storage Disorders Research

Cited by 405

Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms

Wallen, Z. D., Demirkan, A., Twa, G., Cohen, G., Dean, M. N., Standaert, D. G., Sampson, T. R., & Payami, H. (2022) · Nature Communications

Gut microbiota and healthParkinson's Disease Mechanisms and Treatments

Cited by 346

Alpha synuclein overexpression can drive microbiome dysbiosis in mice

Sampson, T. R., Wallen, Z. D., Won, W.-J., Standaert, D. G., Payami, H., & Harms, A. S. (2025) · Scientific Reports

Gut microbiota and healthParkinson's Disease Mechanisms and Treatments

Cited by 11