Dawson, Mark A.

Cancer epigenetics: from mechanism to therapy

Dawson, M. A., & Kouzarides, T. (2012) · Cell

Epigenetics and DNA MethylationChromatin Remodeling and Cancer

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CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity

Burr, M. L., Sparbier, C. E., Chan, Y.-C., Williamson, J. C., Woods, K., Beavis, P. A., Lam, E. Y. N., Henderson, M. A., Bell, C. C., Stolzenburg, S., et al. (2017) · Nature

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 946

The roles of DNA, RNA and histone methylation in ageing and cancer

Michalak, E. M., Burr, M. L., Bannister, A. J., & Dawson, M. A. (2019) · Nature Reviews Molecular Cell Biology

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 549

BET inhibitor resistance emerges from leukaemia stem cells

Fong, C. Y., Gilan, O., Lam, E. Y. N., Rubin, A. F., Ftouni, S., Tyler, D., Stanley, K., Sinha, D., Yeh, P., Morison, J., et al. (2015) · Nature

Protein Degradation and InhibitorsChromatin Remodeling and Cancer

Cited by 545

The cancer epigenome: Concepts, challenges, and therapeutic opportunities

Dawson, M. A. (2017) · Science

Epigenetics and DNA MethylationChromatin Remodeling and Cancer

Cited by 377

Click chemistry enables preclinical evaluation of targeted epigenetic therapies

Tyler, D. S., Vappiani, J., Cañeque, T., Lam, E. Y. N., Ward, A., Gilan, O., Chan, Y.-C., Hienzsch, A., Rutkowska, A., Werner, T., et al. (2017) · Science

Protein Degradation and InhibitorsClick Chemistry and Applications

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HIV is associated with an increased risk of age-related clonal hematopoiesis among older adults

Dharan, N. J., Yeh, P., Bloch, M., Yeung, M. M., Baker, D., Guinto, J., Roth, N., Ftouni, S., Ognenovska, K., Smith, D., et al. (2021) · Nature Medicine

Acute Myeloid Leukemia ResearchHIV-related health complications and treatments

Cited by 108

Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia

McKenzie, M. D., Ghisi, M., Oxley, E. P., Ngo, S., Cimmino, L., Esnault, C., Liu, R., Salmon, J. M., Bell, C. C., Ahmed, N., et al. (2019) · Cell Stem Cell

Acute Myeloid Leukemia ResearchCancer Cells and Metastasis

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Comparative cofactor screens show the influence of transactivation domains and core promoters on the mechanisms of transcription

Bell, C. C., Balic, J. J., Talarmain, L., Gillespie, A., Scolamiero, L., Lam, E. Y. N., Ang, C.-S., Faulkner, G. J., Gilan, O., & Dawson, M. A. (2024) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

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