Dean, Michael

The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

Egan, M. F., Kojima, M., Callicott, J. H., Goldberg, T. E., Kolachana, B. S., Bertolino, A., Zaitsev, E., Gold, B., Goldman, D., Dean, M., et al. (2003) · Cell

Nerve injury and regenerationMemory and Neural Mechanisms

Cited by 3,888

Tumour stem cells and drug resistance

Dean, M., Fojo, T., & Bates, S. (2005) · Nature reviews. Cancer

Cancer Cells and MetastasisDrug Transport and Resistance Mechanisms

Cited by 3,668

A common haplotype in the complement regulatory gene factor H ( HF1/CFH ) predisposes individuals to age-related macular degeneration

Hageman, G. S., Anderson, D. H., Johnson, L. V., Hancox, L. S., Taiber, A. J., Hardisty, L. I., Hageman, J. L., Stockman, H. A., Borchardt, J. D., Gehrs, K. M., et al. (2005) · Proceedings of the National Academy of Sciences

Retinal Diseases and TreatmentsComplement system in diseases

Cited by 1,961

A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Starqardt macular dystrophy

Allikmets, R., Singh, N., Sun, H., Shroyer, N. F., Hutchinson, A., Chidambaram, A., Gerrard, B., Baird, L., Stauffer, D., Peiffer, A., et al. (1997) · Nature Genetics

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 1,435

The human ATP-binding cassette (ABC) transporter superfamily

Dean, M., Hamon, Y., & Chimini, G. (2001) · Journal of Lipid Research

Drug Transport and Resistance MechanismsATP Synthase and ATPases Research

Cited by 1,302

The Genome of the Sea Urchin Strongylocentrotus purpuratus

Sodergren, E., Weinstock, G. M., Davidson, E. H., Cameron, R. A., Gibbs, R. A., Angerer, R. C., Angerer, L. M., Arnone, M. I., Burgess, D. R., Burke, R. D., et al. (2006) · Science

Genomics and Phylogenetic StudiesDevelopmental Biology and Gene Regulation

Cited by 1,132

Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration

The AMD Genetics Clinical Study Group, Gold, B., Merriam, J. E., Zernant, J., Hancox, L. S., Taiber, A. J., Gehrs, K., Cramer, K., Neel, J., Bergeron, J., et al. (2006) · Nature Genetics

Retinal Diseases and TreatmentsComplement system in diseases

Cited by 1,075

Single-Cell Exome Sequencing Reveals Single-Nucleotide Mutation Characteristics of a Kidney Tumor

Xu, X., Hou, Y., Yin, X., Bao, L., Tang, A., Song, L., Li, F., Tsang, S., Wu, K., Wu, H., et al. (2012) · Cell

Cancer Genomics and DiagnosticsRenal cell carcinoma treatment

Cited by 667

Detectable clonal mosaicism and its relationship to aging and cancer

Jacobs, K. B., Yeager, M., Zhou, W., Wacholder, S., Wang, Z., Rodriguez-Santiago, B., Hutchinson, A., Deng, X., Liu, C., Horner, M.-J., et al. (2012) · Nature Genetics

Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities

Cited by 589

Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome

Lombardi, V. C., Ruscetti, F. W., Das Gupta, J., Pfost, M. A., Hagen, K. S., Peterson, D. L., Ruscetti, S. K., Bagni, R. K., Petrow-Sadowski, C., Gold, B., et al. (2009) · Science

Fibromyalgia and Chronic Fatigue Syndrome ResearchT-cell and Retrovirus Studies

Cited by 538

Dating the Origin of the CCR5-Δ32 AIDS-Resistance Allele by the Coalescence of Haplotypes

Stephens, J. C., Reich, D. E., Goldstein, D. B., Shin, H. D., Smith, M. W., Carrington, M., Winkler, C., Huttley, G. A., Allikmets, R., Schriml, L., et al. (1998) · The American Journal of Human Genetics

HIV Research and TreatmentForensic and Genetic Research

Cited by 520

The chemical defensome: Environmental sensing and response genes in the Strongylocentrotus purpuratus genome

Goldstone, J. V., Hamdoun, A., Cole, B. J., Howard-Ashby, M., Nebert, D. W., Scally, M., Dean, M., Epel, D., Hahn, M. E., & Stegeman, J. J. (2006) · Developmental Biology

Environmental Toxicology and EcotoxicologyDevelopmental Biology and Gene Regulation

Cited by 280

Multidrug Efflux Pumps and Cancer Stem Cells: Insights Into Multidrug Resistance and Therapeutic Development

Moitra, K., Lou, H., & Dean, M. (2011) · Clinical Pharmacology & Therapeutics

Drug Transport and Resistance MechanismsCancer Cells and Metastasis

Cited by 279

Frequency of Pathogenic Germline Variants in Cancer-Susceptibility Genes in Patients With Osteosarcoma

Mirabello, L., Zhu, B., Koster, R., Karlins, E., Dean, M., Yeager, M., Gianferante, M., Spector, L. G., Morton, L. M., Karyadi, D., et al. (2020) · JAMA Oncology

Sarcoma Diagnosis and TreatmentBRCA gene mutations in cancer

Cited by 243

Evolution of the vertebrate ABC gene family: analysis of gene birth and death

Annilo, T., Chen, Z.-Q., Shulenin, S., Costantino, J., Thomas, L., Lou, H., Stefanov, S., & Dean, M. (2006) · Genomics

Drug Transport and Resistance MechanismsGenomics and Phylogenetic Studies

Cited by 175

Evidence of association of APOE with age-related macular degeneration - a pooled analysis of 15 studies

McKay, G. J., Patterson, C. C., Chakravarthy, U., Dasari, S., Klaver, C. C., Vingerling, J. R., Ho, L., de Jong, P. T. V. M., Fletcher, A. E., Young, I. S., et al. (2011) · Human Mutation

Retinal Diseases and TreatmentsRetinal Imaging and Analysis

Cited by 151

Variations in Apolipoprotein E Frequency With Age in a Pooled Analysis of a Large Group of Older People

McKay, G. J., Silvestri, G., Chakravarthy, U., Dasari, S., Fritsche, L. G., Weber, B. H., Keilhauer, C. N., Klein, M. L., Francis, P. J., Klaver, C. C., et al. (2011) · American Journal of Epidemiology

Lipoproteins and Cardiovascular HealthRetinal Diseases and Treatments

Cited by 105

Genome Analysis of Latin American Cervical Cancer: Frequent Activation of the PIK3CA Pathway

Lou, H., Villagran, G., Boland, J. F., Im, K. M., Polo, S., Zhou, W., Odey, U., Juárez-Torres, E., Medina-Martínez, I., Roman-Basaure, E., et al. (2015) · Clinical Cancer Research

Cervical Cancer and HPV ResearchPI3K/AKT/mTOR signaling in cancer

Cited by 88

Bringing age-related macular degeneration into focus

Allikmets, R., & Dean, M. (2008) · Nature Genetics

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 26