Bacskai, Brian J.

Mitochondrial alterations near amyloid plaques in an Alzheimer’s disease mouse model

Xie, H., Guan, J., Borrelli, L. A., Xu, J., Serrano-Pozo, A., & Bacskai, B. J. (2013) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsMitochondrial Function and Pathology

Cited by 185

In Vivo Imaging of Reactive Oxygen Species Specifically Associated with Thioflavine S-Positive Amyloid Plaques by Multiphoton Microscopy

McLellan, M. E., Kajdasz, S. T., Hyman, B. T., & Bacskai, B. J. (2003) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 174

Rapid cell death is preceded by amyloid plaque-mediated oxidative stress

Xie, H., Hou, S., Jiang, J., Sekutowicz, M., Kelly, J., & Bacskai, B. J. (2013) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsCell death mechanisms and regulation

Cited by 172

Amyloid-β Antibody Treatment Leads to Rapid Normalization of Plaque-Induced Neuritic Alterations

Lombardo, J. A., Stern, E. A., McLellan, M. E., Kajdasz, S. T., Hickey, G. A., Bacskai, B. J., & Hyman, B. T. (2003) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 149

Rapid Microglial Response Around Amyloid Pathology after Systemic Anti-Aβ Antibody Administration in PDAPP Mice

Koenigsknecht-Talboo, J., Meyer-Luehmann, M., Parsadanian, M., Garcia-Alloza, M., Finn, M. B., Hyman, B. T., Bacskai, B. J., & Holtzman, D. M. (2008) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 149

In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons

Spires-Jones, T. L., de Calignon, A., Matsui, T., Zehr, C., Pitstick, R., Wu, H.-Y., Osetek, J. D., Jones, P. B., Bacskai, B. J., Feany, M. B., et al. (2008) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsCell death mechanisms and regulation

Cited by 137

Differential effect of three‐repeat and four‐repeat tau on mitochondrial axonal transport

Stoothoff, W., Jones, P. B., Spires‐Jones, T. L., Joyner, D., Chhabra, E., Bercury, K., Fan, Z., Xie, H., Bacskai, B., Edd, J., et al. (2009) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsAmyotrophic Lateral Sclerosis Research

Cited by 135

Different microvascular alterations underlie microbleeds and microinfarcts

van Veluw, S. J., Scherlek, A. A., Freeze, W. M., ter Telgte, A., van der Kouwe, A. J., Bacskai, B. J., Frosch, M. P., & Greenberg, S. M. (2019) · Annals of Neurology

Intracerebral and Subarachnoid Hemorrhage ResearchCerebrovascular and genetic disorders

Cited by 104

Plaque-derived oxidative stress mediates distorted neurite trajectories in the Alzheimer mouse model

Garcia-Alloza, M., Dodwell, S. A., Meyer-Luehmann, M., Hyman, B. T., & Bacskai, B. J. (2006) · Journal of Neuropathology & Experimental Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 99

Imaging the pathology of Alzheimer's disease: amyloid-imaging with positron emission tomography

Klunk, W. E., Engler, H., Nordberg, A., Bacskai, B. J., Wang, Y., Price, J. C., Bergström, M., Hyman, B. T., Långström, B., & Mathis, C. A. (2003) · Neuroimaging Clinics of North America

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 96

In Vivo Multiphoton Imaging of a Transgenic Mouse Model of Alzheimer Disease Reveals Marked Thioflavine-S-Associated Alterations in Neurite Trajectories

D'Amore, J. D., Kajdasz, S. T., McLellan, M. E., Bacskai, B. J., Stern, E. A., & Hyman, B. T. (2003) · Journal of Neuropathology & Experimental Neurology

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 89

Blood-Brain Barrier Leakage and Microvascular Lesions in Cerebral Amyloid Angiopathy

Freeze, W. M., Bacskai, B. J., Frosch, M. P., Jacobs, H. I. L., Backes, W. H., Greenberg, S. M., & van Veluw, S. J. (2019) · Stroke

Intracerebral and Subarachnoid Hemorrhage ResearchCerebrovascular and genetic disorders

Cited by 85

Apolipoprotein E: isoform specific differences in tertiary structure and interaction with amyloid-β in human Alzheimer brain

Jones, P. B., Adams, K. W., Rozkalne, A., Spires-Jones, T. L., Hshieh, T. T., Hashimoto, T., von Armin, C. A. F., Mielke, M., Bacskai, B. J., & Hyman, B. T. (2011) · PLoS ONE

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 84

Reduced excitatory neuron activity and interneuron-type-specific deficits in a mouse model of Alzheimer’s disease

Algamal, M., Russ, A. N., Miller, M. R., Hou, S. S., Maci, M., Munting, L. P., Zhao, Q., Gerashchenko, D., Bacskai, B. J., & Kastanenka, K. V. (2022) · Communications Biology

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 50

High mitochondrial calcium levels precede neuronal death in vivo in Alzheimer’s disease

Calvo-Rodriguez, M., & Bacskai, B. J. (2020) · Cell Stress

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 27

Monitoring protein aggregation and toxicity in Alzheimer's disease mouse models using in vivo imaging

Spires-Jones, T. L., Calignon, A. D., Meyer-Luehmann, M., Bacskai, B. J., & Hyman, B. T. (2011) · Methods

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 24

Vasomotion loss precedes impaired cerebrovascular reactivity and microbleeds in cerebral amyloid angiopathy

Kozberg, M. G., Munting, L. P., Hanlin, L. H., Auger, C. A., van den Berg, M. L., Denis de Senneville, B., Hirschler, L., Warnking, J. M., Barbier, E. L., Farrar, C. T., et al. (2025) · Brain Communications

Intracerebral and Subarachnoid Hemorrhage ResearchNeurological Disease Mechanisms and Treatments

Cited by 23