Walz, Thomas

The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis

Li, J., McQuade, T., Siemer, A. B., Napetschnig, J., Moriwaki, K., Hsiao, Y.-S., Damko, E., Moquin, D., Walz, T., McDermott, A., et al. (2012) · Cell

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 1,222

Latent TGF-β structure and activation

Shi, M., Zhu, J., Wang, R., Chen, X., Mi, L., Walz, T., & Springer, T. A. (2011) · Nature

TGF-β signaling in diseasesCell Adhesion Molecules Research

Cited by 1,013

Structure of the human transferrin receptor-transferrin complex

Cheng, Y., Zak, O., Aisen, P., Harrison, S. C., & Walz, T. (2004) · Cell

Iron Metabolism and DisordersAdvanced Electron Microscopy Techniques and Applications

Cited by 571

Molecular model for a complete clathrin lattice from electron cryomicroscopy

Fotin, A., Cheng, Y., Sliz, P., Grigorieff, N., Harrison, S. C., Kirchhausen, T., & Walz, T. (2004) · Nature

Cellular transport and secretionAdvanced Electron Microscopy Techniques and Applications

Cited by 541

Covalently circularized nanodiscs for studying membrane proteins and viral entry

Nasr, M. L., Baptista, D., Strauss, M., Sun, Z.-Y. J., Grigoriu, S., Huser, S., Plückthun, A., Hagn, F., Walz, T., Hogle, J. M., et al. (2017) · Nature Methods

Lipid Membrane Structure and BehaviorProtein Structure and Dynamics

Cited by 262

Quaternary Structure, Protein Dynamics, and Synaptic Function of SAP97 Controlled by L27 Domain Interactions

Nakagawa, T., Futai, K., Lashuel, H. A., Lo, I., Okamoto, K., Walz, T., Hayashi, Y., & Sheng, M. (2004) · Neuron

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 250

Rac1 GTPase activates the WAVE regulatory complex through two distinct binding sites

Chen, B., Chou, H.-T., Brautigam, C. A., Xing, W., Yang, S., Henry, L., Doolittle, L. K., Walz, T., & Rosen, M. K. (2017) · eLife

Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions

Cited by 173

Relating conformation to function in integrin α 5 β 1

Su, Y., Xia, W., Li, J., Walz, T., Humphries, M. J., Vestweber, D., Cabañas, C., Lu, C., & Springer, T. A. (2016) · Proceedings of the National Academy of Sciences

Cell Adhesion Molecules ResearchBiochemical and Structural Characterization

Cited by 146

CATCHR, HOPS and CORVET tethering complexes share a similar architecture

Chou, H.-T., Dukovski, D., Chambers, M. G., Reinisch, K. M., & Walz, T. (2016) · Nature Structural & Molecular Biology

Cellular transport and secretionFungal and yeast genetics research

Cited by 83

Allosteric β1 Integrin Antibodies That Stabilize the Low Affinity State by Preventing the Swing-out of the Hybrid Domain

Luo, B.-H., Strokovich, K., Walz, T., Springer, T. A., & Takagi, J. (2004) · Journal of Biological Chemistry

Cell Adhesion Molecules ResearchBiochemical and Structural Characterization

Cited by 73

Shelterin is a dimeric complex with extensive structural heterogeneity

Zinder, J. C., Olinares, P. D. B., Svetlov, V., Bush, M. W., Nudler, E., Chait, B. T., Walz, T., & de Lange, T. (2022) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceDNA and Nucleic Acid Chemistry

Cited by 44

An ensemble of flexible conformations underlies mechanotransduction by the cadherin–catenin adhesion complex

Bush, M., Alhanshali, B. M., Qian, S., Stanley, C. B., Heller, W. T., Matsui, T., Weiss, T. M., Nicholl, I. D., Walz, T., Callaway, D. J. E., et al. (2019) · Proceedings of the National Academy of Sciences

Wnt/β-catenin signaling in development and cancerCellular Mechanics and Interactions

Cited by 42