Schirmer, Lucas

Neurotoxic reactive astrocytes are induced by activated microglia

Liddelow, S. A., Guttenplan, K. A., Clarke, L. E., Bennett, F. C., Bohlen, C. J., Schirmer, L., Bennett, M. L., Münch, A. E., Chung, W.-S., Peterson, T. C., et al. (2017) · Nature

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 7,971

Single-cell genomics identifies cell type–specific molecular changes in autism

Velmeshev, D., Schirmer, L., Jung, D., Haeussler, M., Perez, Y., Mayer, S., Bhaduri, A., Goyal, N., Rowitch, D. H., & Kriegstein, A. R. (2019) · Science

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 927

Neuronal vulnerability and multilineage diversity in multiple sclerosis

Schirmer, L., Velmeshev, D., Holmqvist, S., Kaufmann, M., Werneburg, S., Jung, D., Vistnes, S., Stockley, J. H., Young, A., Steindel, M., et al. (2019) · Nature

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 638

Single-cell analysis of prenatal and postnatal human cortical development

Velmeshev, D., Perez, Y., Yan, Z., Valencia, J. E., Castaneda-Castellanos, D. R., Wang, L., Schirmer, L., Mayer, S., Wick, B., Wang, S., et al. (2023) · Science

Single-cell and spatial transcriptomicsNeurogenesis and neuroplasticity mechanisms

Cited by 204

Reactive astrocyte COX2-PGE2 production inhibits oligodendrocyte maturation in neonatal white matter injury

Shiow, L. R., Favrais, G., Schirmer, L., Schang, A., Cipriani, S., Andres, C., Wright, J. N., Nobuta, H., Fleiss, B., Gressens, P., et al. (2017) · Glia

Neonatal and fetal brain pathologyNeuroinflammation and Neurodegeneration Mechanisms

Cited by 130

Cell type mapping reveals tissue niches and interactions in subcortical multiple sclerosis lesions

Lerma-Martin, C., Badia-i-Mompel, P., Ramirez Flores, R. O., Sekol, P., Schäfer, P. S. L., Riedl, C. J., Hofmann, A., Thäwel, T., Wünnemann, F., Ibarra-Arellano, M. A., et al. (2024) · Nature Neuroscience

Multiple Sclerosis Research StudiesSingle-cell and spatial transcriptomics

Cited by 76

Substantial early, but nonprogressive neuronal loss in multiple sclerosis (ms) spinal cord

Schirmer, L., Albert, M., Buss, A., Schulz‐Schaeffer, W. J., Antel, J. P., Brück, W., & Stadelmann, C. (2009) · Annals of Neurology

Multiple Sclerosis Research StudiesSpinal Cord Injury Research

Cited by 56

Cross-regional homeostatic and reactive glial signatures in multiple sclerosis

Trobisch, T., Zulji, A., Stevens, N. A., Schwarz, S., Wischnewski, S., Öztürk, M., Perales-Patón, J., Haeussler, M., Saez-Rodriguez, J., Velmeshev, D., et al. (2022) · Acta Neuropathologica

Multiple Sclerosis Research StudiesSingle-cell and spatial transcriptomics

Cited by 40

Spatial lipidomics reveals demyelination and remyelination dynamics in the mouse brain

Opielka, M., Urbanowicz, K., Konieczna-Wolska, K., Müller, E., Krajewski, O., Feucherolles, M., Zhou, Q., Bienkowski, M., Frache, G., Hopf, C., et al. (2025) · Journal of Lipid Research

Multiple Sclerosis Research StudiesMetabolomics and Mass Spectrometry Studies

Cited by 8