Roux, Philippe P.

Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases

Cargnello, M., & Roux, P. P. (2011) · Microbiology and Molecular Biology Reviews

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

Cited by 3,274

Neurotrophin Signaling Through the P75 Neurotrophin Receptor

Roux, P. (2002) · Progress in Neurobiology

Nerve injury and regenerationCell death mechanisms and regulation

Cited by 717

ERK1/2 Phosphorylate Raptor to Promote Ras-dependent Activation of mTOR Complex 1 (mTORC1)

Carriere, A., Romeo, Y., Acosta-Jaquez, H. A., Moreau, J., Bonneil, E., Thibault, P., Fingar, D. C., & Roux, P. P. (2011) · Journal of Biological Chemistry

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

Cited by 268

Phosphoproteomic analysis identifies the tumor suppressor PDCD4 as a RSK substrate negatively regulated by 14-3-3

Galan, J. A., Geraghty, K. M., Lavoie, G., Kanshin, E., Tcherkezian, J., Calabrese, V., Jeschke, G. R., Turk, B. E., Ballif, B. A., Blenis, J., et al. (2014) · Proceedings of the National Academy of Sciences

14-3-3 protein interactionsProtein Kinase Regulation and GTPase Signaling

Cited by 85

Mutations in DOCK7 in Individuals with Epileptic Encephalopathy and Cortical Blindness

Perrault, I., Hamdan, F. F., Rio, M., Capo-Chichi, J.-M., Boddaert, N., Décarie, J.-C., Maranda, B., Nabbout, R., Sylvain, M., Lortie, A., et al. (2014) · The American Journal of Human Genetics

Epilepsy research and treatmentGenetics and Neurodevelopmental Disorders

Cited by 50

The CDK12 inhibitor SR-4835 functions as a molecular glue that promotes cyclin K degradation in melanoma

Houles, T., Boucher, J., Lavoie, G., MacLeod, G., Lin, S., Angers, S., & Roux, P. P. (2023) · Cell Death Discovery

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 49

Mind the GAP: Wnt Steps onto the mTORC1 Train

Choo, A. Y., Roux, P. P., & Blenis, J. (2006) · Cell

PI3K/AKT/mTOR signaling in cancerWnt/β-catenin signaling in development and cancer

Cited by 43

RIOK2 phosphorylation by RSK promotes synthesis of the human small ribosomal subunit

Cerezo, E. L., Houles, T., Lié, O., Sarthou, M.-K., Audoynaud, C., Lavoie, G., Halladjian, M., Cantaloube, S., Froment, C., Burlet-Schiltz, O., et al. (2021) · PLOS Genetics

RNA and protein synthesis mechanismsNuclear Structure and Function

Cited by 26