Nigsch, Florian

Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution

Cowan, C. S., Renner, M., De Gennaro, M., Gross-Scherf, B., Goldblum, D., Hou, Y., Munz, M., Rodrigues, T. M., Krol, J., Szikra, T., et al. (2020) · Cell

Retinal Development and DisordersSingle-cell and spatial transcriptomics

Cited by 654

The RSPO–LGR4/5–ZNRF3/RNF43 module controls liver zonation and size

Planas-Paz, L., Orsini, V., Boulter, L., Calabrese, D., Pikiolek, M., Nigsch, F., Xie, Y., Roma, G., Donovan, A., Marti, P., et al. (2016) · Nature Cell Biology

Wnt/β-catenin signaling in development and cancerLiver physiology and pathology

Cited by 359

YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury

Planas-Paz, L., Sun, T., Pikiolek, M., Cochran, N. R., Bergling, S., Orsini, V., Yang, Z., Sigoillot, F., Jetzer, J., Syed, M., et al. (2019) · Cell Stem Cell

Liver physiology and pathologyWnt/β-catenin signaling in development and cancer

Cited by 216

High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions

Hoepfner, D., Helliwell, S. B., Sadlish, H., Schuierer, S., Filipuzzi, I., Brachat, S., Bhullar, B., Plikat, U., Abraham, Y., Altorfer, M., et al. (2014) · Microbiological Research

Fungal and yeast genetics researchBioinformatics and Genomic Networks

Cited by 166

Single-cell and bulk transcriptomics of the liver reveals potential targets of NASH with fibrosis

Wang, Z.-Y., Keogh, A., Waldt, A., Cuttat, R., Neri, M., Zhu, S., Schuierer, S., Ruchti, A., Crochemore, C., Knehr, J., et al. (2021) · Scientific Reports

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 103

Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy

Potting, C., Crochemore, C., Moretti, F., Nigsch, F., Schmidt, I., Manneville, C., Carbone, W., Knehr, J., DeJesus, R., Lindeman, A., et al. (2018) · Proceedings of the National Academy of Sciences

Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments

Cited by 93

Loss of Hepatic Leucine-Rich Repeat-Containing G-Protein Coupled Receptors 4 and 5 Promotes Nonalcoholic Fatty Liver Disease

Saponara, E., Penno, C., Orsini, V., Wang, Z.-Y., Fischer, A., Aebi, A., Matadamas-Guzman, M. L., Brun, V., Fischer, B., Brousseau, M., et al. (2023) · The American Journal of Pathology

Liver Disease Diagnosis and TreatmentWnt/β-catenin signaling in development and cancer

Cited by 22