Cerchietti, Leandro

A Small-Molecule Inhibitor of BCL6 Kills DLBCL Cells In Vitro and In Vivo

Cerchietti, L. C., Ghetu, A. F., Zhu, X., Da Silva, G. F., Zhong, S., Matthews, M., Bunting, K. L., Polo, J. M., Farès, C., Arrowsmith, C. H., et al. (2010) · Cancer Cell

Lymphoma Diagnosis and TreatmentProtein Degradation and Inhibitors

Cited by 288

Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma

Cardenas, M. G., Yu, W., Beguelin, W., Teater, M. R., Geng, H., Goldstein, R. L., Oswald, E., Hatzi, K., Yang, S.-N., Cohen, J., et al. (2016) · Journal of Clinical Investigation

Lymphoma Diagnosis and TreatmentComputational Drug Discovery Methods

Cited by 176

Structure of a BCOR Corepressor Peptide in Complex with the BCL6 BTB Domain Dimer

Ghetu, A. F., Corcoran, C. M., Cerchietti, L., Bardwell, V. J., Melnick, A., & Privé, G. G. (2008) · Molecular Cell

Genomics and Chromatin DynamicsProtein Structure and Dynamics

Cited by 168

Precise reconstruction of the TME using bulk RNA-seq and a machine learning algorithm trained on artificial transcriptomes

Zaitsev, A., Chelushkin, M., Dyikanov, D., Cheremushkin, I., Shpak, B., Nomie, K., Zyrin, V., Nuzhdina, E., Lozinsky, Y., Zotova, A., et al. (2022) · Cancer Cell

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 139

Microenvironmental Signatures Reveal Biological Subtypes of Diffuse Large B-Cell Lymphoma (DLBCL) Distinct from Tumor Cell Molecular Profiling

Cerchietti, L., Inghirami, G., Kotlov, N., Svekolkin, V., Bagaev, A., Frenkel, F., Revuelta, M. V., Phillip, J. M., Cacciapuoti, M. T., Rutherford, S. C., et al. (2019) · Blood

Lymphoma Diagnosis and TreatmentViral-associated cancers and disorders

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