Giordano, Silvia

Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

Pennacchietti, S., Michieli, P., Galluzzo, M., Mazzone, M., Giordano, S., & Comoglio, P. M. (2003) · Cancer Cell

Cancer, Hypoxia, and MetabolismLiver physiology and pathology

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Amplification of the MET Receptor Drives Resistance to Anti-EGFR Therapies in Colorectal Cancer

Bardelli, A., Corso, S., Bertotti, A., Hobor, S., Valtorta, E., Siravegna, G., Sartore-Bianchi, A., Scala, E., Cassingena, A., Zecchin, D., et al. (2013) · Cancer Discovery

Colorectal Cancer Treatments and StudiesLung Cancer Treatments and Mutations

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The Dual Roles of NRF2 in Cancer

Menegon, S., Columbano, A., & Giordano, S. (2016) · Trends in Molecular Medicine

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

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Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies

Apicella, M., Giannoni, E., Fiore, S., Ferrari, K. J., Fernández-Pérez, D., Isella, C., Granchi, C., Minutolo, F., Sottile, A., Comoglio, P. M., et al. (2018) · Cell Metabolism

Cancer, Hypoxia, and MetabolismLung Cancer Treatments and Mutations

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Yes-associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice

Kowalik, M. A., Saliba, C., Pibiri, M., Perra, A., Ledda-Columbano, G. M., Sarotto, I., Ghiso, E., Giordano, S., & Columbano, A. (2011) · Hepatology

Hippo pathway signaling and YAP/TAZLiver physiology and pathology

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Thyroid hormone inhibits hepatocellular carcinoma progression via induction of differentiation and metabolic reprogramming

Kowalik, M. A., Puliga, E., Cabras, L., Sulas, P., Petrelli, A., Perra, A., Ledda-Columbano, G. M., Morandi, A., Merlin, S., Orrù, C., et al. (2020) · Journal of Hepatology

Hepatocellular Carcinoma Treatment and PrognosisLiver physiology and pathology

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BRAF and MEK inhibitors increase PD-1-positive melanoma cells leading to a potential lymphocyte-independent synergism with anti-PD-1 antibody

Sanlorenzo, M., Vujic, I., Floris, A., Novelli, M., Gammaitoni, L., Giraudo, L., Macagno, M., Leuci, V., Rotolo, R., Donini, C., et al. (2018) · Clinical Cancer Research

Cancer Immunotherapy and BiomarkersMelanoma and MAPK Pathways

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