Mosley, Amber L.

Delayed Correlation of mRNA and Protein Expression in Rapamycin-treated Cells and a Role for Ggc1 in Cellular Sensitivity to Rapamycin

Fournier, M. L., Paulson, A., Pavelka, N., Mosley, A. L., Gaudenz, K., Bradford, W. D., Glynn, E., Li, H., Sardiu, M. E., Fleharty, B., et al. (2010) · Molecular & Cellular Proteomics

PI3K/AKT/mTOR signaling in cancerFungal and yeast genetics research

Cited by 161

Bassoon contributes to tau-seed propagation and neurotoxicity

Martinez, P., Patel, H., You, Y., Jury, N., Perkins, A., Lee-Gosselin, A., Taylor, X., You, Y., Viana Di Prisco, G., Huang, X., et al. (2022) · Nature Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 68

The Exosome Component Rrp6 Is Required for RNA Polymerase II Termination at Specific Targets of the Nrd1-Nab3 Pathway

Fox, M. J., Gao, H., Smith-Kinnaman, W. R., Liu, Y., & Mosley, A. L. (2015) · PLOS Genetics

RNA Research and SplicingGenomics and Chromatin Dynamics

Cited by 61

Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors

Bellail, A. C., Jin, H. R., Lo, H.-Y., Jung, S. H., Hamdouchi, C., Kim, D., Higgins, R. K., Blanck, M., le Sage, C., Cross, B. C. S., et al. (2021) · Science Translational Medicine

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 42

Temperature sensitive Mutant Proteome Profiling: a novel tool for the characterization of the global impact of missense mutations on the proteome

Peck Justice, S. A., Qi, G., Wijeratne, H. R. S., Victorino, J. F., Simpson, E. R., Wijeratne, A. B., & Mosley, A. L. (2019) · Journal of Biological Chemistry

Advanced Proteomics Techniques and ApplicationsHeat shock proteins research

Cited by 28

Mutant thermal proteome profiling for characterization of missense protein variants and their associated phenotypes within the proteome

Peck Justice, S. A., Barron, M. P., Qi, G. D., Wijeratne, H. R. S., Victorino, J. F., Simpson, E. R., Vilseck, J. Z., Wijeratne, A. B., & Mosley, A. L. (2020) · Journal of Biological Chemistry

Advanced Proteomics Techniques and ApplicationsHeat shock proteins research

Cited by 28

Loss of succinyl-CoA synthetase in mouse forebrain results in hypersuccinylation with perturbed neuronal transcription and metabolism

Lancaster, M. S., Kim, B., Doud, E. H., Tate, M. D., Sharify, A. D., Gao, H., Chen, D., Simpson, E., Gillespie, P., Chu, X., et al. (2023) · Cell Reports

Metabolism and Genetic DisordersMitochondrial Function and Pathology

Cited by 24

Deletion of miR-33, a regulator of the ABCA1–APOE pathway, ameliorates neuropathological phenotypes in APP/PS1 mice

Tate, M., Wijeratne, H. R. S., Kim, B., Philtjens, S., You, Y., Lee, D., Gutierrez, D. A., Sharify, D., Wells, M., Perez‐Cardelo, M., et al. (2024) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 21

Deletion of SPI1 in microglia exacerbates amyloid pathology by impairing microglial response in Alzheimer’s disease models

Kim, B., Tate, M. D., Karahan, H., Wijeratne, H. R. S., Sharify, A. D., Wang, S. S., Kim, J. R., Al-Amin, M. M., Hartigan, K., Chung, S., et al. (2026) · Neuron

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 6

EXOSC3 S1-domain variants implicated in PCH1b alter RNA exosome cap subunit abundance and thermal stability disrupting rRNA processing and targeting of AU-rich mRNA

Runnebohm, A. M., Wijeratne, H. R. S., Barron, M. P., Smith-Kinnaman, W. R., Rooney, J. D., Peck Justice, S. A., Cureton, L. A., Holland, A., Ghalei, H., Pelletier, S., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory)

RNA Research and SplicingGenomics and Rare Diseases

Cited by 4

EXOSC3 G191 Variants Trigger System-Wide Recalibration of RNA Processing Machinery

Wijeratne, H. R. S., Runnebohm, A. M., Barron, M. P., Hampton, A. J., Li, R., Peck Justice, S. A., Lenceski, S. H., Rooney, J. D., Smith-Kinnaman, W. R., Chang, G. S., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory)

RNA Research and SplicingGenomics and Rare Diseases

Cited by 1

Quantifying the Structural and Energetic Consequences of EXOSC3 S1 Domain Variants from a Comparative Assessment of λ-Dynamics with Two Charge-Changing Perturbation Strategies

Barron, M. P., Wijeratne, H. R. S., Runnebohm, A. M., Caric, K. M., Mosley, A. L., & Vilseck, J. Z. (2025) · bioRxiv (Cold Spring Harbor Laboratory)

Protein Structure and DynamicsComputational Drug Discovery Methods

Cited by 1