Bouwman, Peter

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

Bouwman, P., Aly, A., Escandell, J. M., Pieterse, M., Bartkova, J., van der Gulden, H., Hiddingh, S., Thanasoula, M., Kulkarni, A., Yang, Q., et al. (2010) · Nature Structural & Molecular Biology

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 1,001

PARP inhibitor efficacy depends on CD8(+) T-cell recruitment via intratumoral STING pathway activation in BRCA-deficient models of triple-negative breast cancer

Pantelidou, C., Sonzogni, O., De Oliveria Taveira, M., Mehta, A. K., Kothari, A., Wang, D., Visal, T., Li, M. K., Pinto, J., Castrillon, J. A., et al. (2019) · Cancer Discovery

PARP inhibition in cancer therapyCancer Immunotherapy and Biomarkers

Cited by 743

The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance

Bouwman, P., & Jonkers, J. (2012) · Nature Reviews Cancer

DNA Repair MechanismsPARP inhibition in cancer therapy

Cited by 615

BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival

Gorrini, C., Baniasadi, P. S., Harris, I. S., Silvester, J., Inoue, S., Snow, B., Joshi, P. A., Wakeham, A., Molyneux, S. D., Martin, B., et al. (2013) · Journal of Experimental Medicine

Genomics, phytochemicals, and oxidative stressBRCA gene mutations in cancer

Cited by 289

A High-Throughput Functional Complementation Assay for Classification of BRCA1 Missense Variants

Bouwman, P., van der Gulden, H., van der Heijden, I., Drost, R., Klijn, C. N., Prasetyanti, P., Pieterse, M., Wientjens, E., Seibler, J., Hogervorst, F. B. L., et al. (2013) · Cancer Discovery

BRCA gene mutations in cancerGenomics and Rare Diseases

Cited by 140

BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny

Sotiropoulou, P. A., Karambelas, A. E., Debaugnies, M., Candi, A., Bouwman, P., Moers, V., Revenco, T., Rocha, A. S., Sekiguchi, K., Jonkers, J., et al. (2013) · Genes & Development

Hair Growth and DisordersSkin and Cellular Biology Research

Cited by 42