Sinning, Irmgard

Crystal structure of the NG domain from the signal-recognition particle receptor FtsY.

Montoya, G., Svensson, C., Luirink, J., & Sinning, I. (1997) · Nature

RNA and protein synthesis mechanismsCellular transport and secretion

Cited by 210

Distinct modes of signal recognition particle interaction with the ribosome.

Pool, M. R., Stumm, J., Fulga, T. A., Sinning, I., & Dobberstein, B. (2002) · Science

RNA and protein synthesis mechanismsCellular transport and secretion

Cited by 199

Structural and molecular mechanisms for membrane protein biogenesis by the Oxa1 superfamily.

McDowell, M. A., Heimes, M., & Sinning, I. (2021) · Nature Structural & Molecular Biology

Lipid Membrane Structure and BehaviorProtein Structure and Dynamics

Cited by 66

The crystal structure of the periplasmic domain of the Escherichia coli membrane protein insertase YidC contains a substrate binding cleft.

Ravaud, S., Stjepanovic, G., Wild, K., & Sinning, I. (2008) · Journal of Biological Chemistry

Bacterial Genetics and BiotechnologyEnzyme Structure and Function

Cited by 59

Multi-protein assemblies orchestrate co-translational enzymatic processing on the human ribosome

Klein, M., Wild, K., & Sinning, I. (2024) · Nature Communications

RNA and protein synthesis mechanismsRNA modifications and cancer

Cited by 24

Multi-protein assemblies orchestrate co-translational enzymatic processing on the human ribosome

Klein, M., Wild, K., & Sinning, I. (2024) · Nature Communications

RNA and protein synthesis mechanismsRNA modifications and cancer

Cited by 24

The Listeria monocytogenes persistence factor ClpL is a potent stand-alone disaggregase

Bohl, V., Hollmann, N. M., Melzer, T., Katikaridis, P., Meins, L., Simon, B., Flemming, D., Sinning, I., Hennig, J., & Mogk, A. (2024) · eLife

Heat shock proteins researchBacterial Genetics and Biotechnology

Cited by 14

The Listeria monocytogenes persistence factor ClpL is a potent stand-alone disaggregase

Bohl, V., Hollmann, N. M., Melzer, T., Katikaridis, P., Meins, L., Simon, B., Flemming, D., Sinning, I., Hennig, J., & Mogk, A. (2023) · eLife

Heat shock proteins researchBacterial Genetics and Biotechnology

Cited by 14

The Listeria monocytogenes persistence factor ClpL is a potent stand-alone disaggregase

Bohl, V., Hollmann, N. M., Melzer, T., Katikaridis, P., Meins, L., Simon, B., Flemming, D., Sinning, I., Hennig, J., & Mogk, A. (2024) · eLife

Heat shock proteins researchBacterial Genetics and Biotechnology

Cited by 14

Structures of aberrant spliceosome intermediates on their way to disassembly

Soni, K., Horvath, A., Dybkov, O., Schwan, M., Trakansuebkul, S., Flemming, D., Wild, K., Urlaub, H., Fischer, T., & Sinning, I. (2025) · Nature Structural & Molecular Biology

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 14

The Listeria monocytogenes persistence factor ClpL is a potent stand-alone disaggregase

Bohl, V., Hollmann, N. M., Melzer, T., Katikaridis, P., Meins, L., Simon, B., Flemming, D., Sinning, I., Hennig, J., & Mogk, A. (2024) · eLife

Heat shock proteins researchBacterial Genetics and Biotechnology

Cited by 14

DNA-encoded library screening uncovers potent DNMT2 inhibitors targeting a cryptic allosteric binding site

Frey, A. F., Schwan, M., Weldert, A. C., Kadenbach, V., Kopp, J., Nidoieva, Z., Zimmermann, R. A., Gleue, L., Zimmer, C., Jörg, M., et al. (2025) · iScience

RNA modifications and cancerEpigenetics and DNA Methylation

Cited by 5