Uhlén, Mathias

Tissue-based map of the human proteome

Uhlén, M., Fagerberg, L., Hallström, B. M., Lindskog, C., Oksvold, P., Mardinoglu, A., Sivertsson, Å., Kampf, C., Sjöstedt, E., Asplund, A., et al. (2015) · Science

Bioinformatics and Genomic NetworksAdvanced Proteomics Techniques and Applications

Cited by 15,286

Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics

Fagerberg, L., Hallström, B. M., Oksvold, P., Kampf, C., Djureinovic, D., Odeberg, J., Habuka, M., Tahmasebpoor, S., Danielsson, A., Edlund, K., et al. (2014) · Molecular & Cellular Proteomics

Bioinformatics and Genomic NetworksGene expression and cancer classification

Cited by 3,665

A subcellular map of the human proteome

Thul, P. J., Åkesson, L., Wiking, M., Mahdessian, D., Geladaki, A., Ait Blal, H., Alm, T., Asplund, A., Björk, L., Breckels, L. M., et al. (2017) · Science

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 2,813

Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays

Chen, A., Liao, S., Cheng, M., Ma, K., Wu, L., Lai, Y., Qiu, X., Yang, J., Xu, J., Hao, S., et al. (2022) · Cell

Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation

Cited by 1,784

A single–cell type transcriptomics map of human tissues

Karlsson, M., Zhang, C., Méar, L., Zhong, W., Digre, A., Katona, B., Sjöstedt, E., Butler, L., Odeberg, J., Dusart, P., et al. (2021) · Science Advances

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 1,768

An atlas of the protein-coding genes in the human, pig, and mouse brain

Sjöstedt, E., Zhong, W., Fagerberg, L., Karlsson, M., Mitsios, N., Adori, C., Oksvold, P., Edfors, F., Limiszewska, A., Hikmet, F., et al. (2020) · Science

Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks

Cited by 1,151

The protein expression profile of ACE2 in human tissues

Hikmet, F., Méar, L., Edvinsson, Å., Micke, P., Uhlén, M., & Lindskog, C. (2020) · Molecular Systems Biology

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 1,016

How many human proteoforms are there?

Aebersold, R., Agar, J. N., Amster, I. J., Baker, M. S., Bertozzi, C. R., Boja, E. S., Costello, C. E., Cravatt, B. F., Fenselau, C., Garcia, B. A., et al. (2018) · Nature Chemical Biology

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 907

Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes

Romanov, R. A., Zeisel, A., Bakker, J., Girach, F., Hellysaz, A., Tomer, R., Alpár, A., Mulder, J., Clotman, F., Keimpema, E., et al. (2017) · Nature Neuroscience

Single-cell and spatial transcriptomicsCircadian rhythm and melatonin

Cited by 502

The human secretome

Uhlén, M., Karlsson, M. J., Hober, A., Svensson, A.-S., Scheffel, J., Kotol, D., Zhong, W., Tebani, A., Strandberg, L., Edfors, F., et al. (2019) · Science Signaling

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 495

Gene‐specific correlation of RNA and protein levels in human cells and tissues

Edfors, F., Danielsson, F., Hallström, B. M., Käll, L., Lundberg, E., Pontén, F., Forsström, B., & Uhlén, M. (2016) · Molecular Systems Biology

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 493

An atlas of human metabolism

Robinson, J. L., Kocabaş, P., Wang, H., Cholley, P.-E., Cook, D., Nilsson, A., Anton, M., Ferreira, R., Domenzain, I., Billa, V., et al. (2020) · Science Signaling

Microbial Metabolic Engineering and BioproductionBioinformatics and Genomic Networks

Cited by 442

The human proteome project: current state and future direction

Legrain, P., Aebersold, R., Archakov, A., Bairoch, A., Bala, K., Beretta, L., Bergeron, J., Borchers, C. H., Corthals, G. L., Costello, C. E., et al. (2011) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 352

Targeting HMG-CoA reductase with statins in a window-of-opportunity breast cancer trial

Bjarnadottir, O., Romero, Q., Bendahl, P.-O., Jirström, K., Rydén, L., Loman, N., Uhlén, M., Johannesson, H., Rose, C., Grabau, D., et al. (2013) · Breast Cancer Research and Treatment

Cancer, Lipids, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 230

A global view of protein expression in human cells, tissues, and organs

Pontén, F., Gry, M., Fagerberg, L., Lundberg, E., Asplund, A., Berglund, L., Oksvold, P., Björling, E., Hober, S., Kampf, C., et al. (2009) · Molecular Systems Biology

Bioinformatics and Genomic NetworksAdvanced Proteomics Techniques and Applications

Cited by 222

A high-stringency blueprint of the human proteome

Adhikari, S., Nice, E. C., Deutsch, E. W., Lane, L., Omenn, G. S., Pennington, S. R., Paik, Y.-K., Overall, C. M., Corrales, F. J., Cristea, I. M., et al. (2020) · Nature Communications

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 210

Altered perivascular fibroblast activity precedes ALS disease onset

Månberg, A., Skene, N., Sanders, F., Trusohamn, M., Remnestål, J., Szczepińska, A., Aksoylu, I. S., Lönnerberg, P., Ebarasi, L., Wouters, S., et al. (2021) · Nature Medicine

Amyotrophic Lateral Sclerosis ResearchMultiple Sclerosis Research Studies

Cited by 120

Anoctamin 2 identified as an autoimmune target in multiple sclerosis

Ayoglu, B., Mitsios, N., Kockum, I., Khademi, M., Zandian, A., Sjöberg, R., Forsström, B., Bredenberg, J., Lima Bomfim, I., Holmgren, E., et al. (2016) · Proceedings of the National Academy of Sciences

Multiple Sclerosis Research StudiesSystemic Lupus Erythematosus Research

Cited by 111

What Is Your Conceptual Definition of “Cell Type” in the Context of a Mature Organism?

Clevers, H., Rafelski, S., Elowitz, M. B., Klein, A., Shendure, J., Trapnell, C., Lein, E., Lundberg, E. K., Uhlén, M., Martinez-Arias, A., et al. (2017) · Cell Systems

Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation

Cited by 108

Disorganization and degeneration of liver sympathetic innervations in nonalcoholic fatty liver disease revealed by 3D imaging

Adori, C., Daraio, T., Kuiper, R., Barde, S., Horvathova, L., Yoshitake, T., Ihnatko, R., Valladolid-Acebes, I., Vercruysse, P., Wellendorf, A. M., et al. (2021) · Science Advances

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 105

Combined Metabolic Activators Accelerates Recovery in Mild‐to‐Moderate COVID‐19

Altay, O., Arif, M., Li, X., Yang, H., Aydın, M., Alkurt, G., Kim, W., Akyol, D., Zhang, C., Dinler‐Doganay, G., et al. (2021) · Advanced Science

COVID-19 Clinical Research StudiesLong-Term Effects of COVID-19

Cited by 88

Combined metabolic activators improve cognitive functions in Alzheimer’s disease patients: a randomised, double-blinded, placebo-controlled phase-II trial

Yulug, B., Altay, O., Li, X., Hanoglu, L., Cankaya, S., Lam, S., Velioglu, H. A., Yang, H., Coskun, E., Idil, E., et al. (2023) · Translational Neurodegeneration

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 79

Altered levels of CSF proteins in patients with FTD, presymptomatic mutation carriers and non-carriers

Remnestål, J., Öijerstedt, L., Ullgren, A., Olofsson, J., Bergström, S., Kultima, K., Ingelsson, M., Kilander, L., Uhlén, M., Månberg, A., et al. (2020) · Translational Neurodegeneration

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 56

Multi-omics analysis reveals the key factors involved in the severity of the Alzheimer’s disease

Meng, L., Jin, H., Yulug, B., Altay, O., Li, X., Hanoglu, L., Cankaya, S., Coskun, E., Idil, E., Nogaylar, R., et al. (2024) · Alzheimer's Research & Therapy

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 49