Hellerbrand, Claus

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

Godoy, P., Hewitt, N. J., Albrecht, U., Andersen, M. E., Ansari, N., Bhattacharya, S., Bode, J. G., Bolleyn, J., Borner, C., Böttger, J., et al. (2013) · Archives of Toxicology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 1,280

A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

Buch, S., Stickel, F., Trépo, E., Way, M., Herrmann, A., Nischalke, H. D., Brosch, M., Rosendahl, J., Berg, T., Ridinger, M., et al. (2015) · Nature Genetics

Alcohol Consumption and Health EffectsGenetic Associations and Epidemiology

Cited by 565

Therapeutic inhibition of inflammatory monocyte recruitment reduces steatohepatitis and liver fibrosis

Krenkel, O., Puengel, T., Govaere, O., Abdallah, A. T., Mossanen, J. C., Kohlhepp, M., Liepelt, A., Lefebvre, E., Luedde, T., Hellerbrand, C., et al. (2018) · Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 557

The role of TGFβ1 in initiating hepatic stellate cell activation in vivo

Hellerbrand, C., Stefanovic, B., Giordano, F., Burchardt, E. R., & Brenner, D. A. (1999) · Journal of Hepatology

Liver physiology and pathologyTGF-β signaling in diseases

Cited by 393

PD-L1 is induced in hepatocytes by viral infection and by interferon-α and -γ and mediates T cell apoptosis

Mühlbauer, M., Fleck, M., Schütz, C., Weiss, T., Froh, M., Blank, C., Schölmerich, J., & Hellerbrand, C. (2006) · Journal of Hepatology

Cancer Immunotherapy and BiomarkersLiver Diseases and Immunity

Cited by 378

DSS induced colitis increases portal LPS levels and enhances hepatic inflammation and fibrogenesis in experimental NASH

Gäbele, E., Dostert, K., Hofmann, C., Wiest, R., Schölmerich, J., Hellerbrand, C., & Obermeier, F. (2011) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 324

Deficiency of intestinal mucin-2 ameliorates experimental alcoholic liver disease in mice

Hartmann, P., Chen, P., Wang, H. J., Wang, L., McCole, D. F., Brandl, K., Stärkel, P., Belzer, C., Hellerbrand, C., Tsukamoto, H., et al. (2013) · Hepatology

Alcohol Consumption and Health EffectsGut microbiota and health

Cited by 246

Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From Patients

Teufel, A., Itzel, T., Erhart, W., Brosch, M., Wang, X. Y., Kim, Y. O., von Schönfels, W., Herrmann, A., Brückner, S., Stickel, F., et al. (2016) · Gastroenterology

Liver Disease Diagnosis and TreatmentDiet, Metabolism, and Disease

Cited by 229

Association between serum ferritin and the insulin resistance syndrome in a representative population

Wrede, C. E., Buettner, R., Bollheimer, L. C., Schölmerich, J., Palitzsch, K.-D., & Hellerbrand, C. (2006) · European Journal of Endocrinology

Iron Metabolism and DisordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 161

Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen

Siegert, I., Schödel, J., Nairz, M., Schatz, V., Dettmer, K., Dick, C., Kalucka, J., Franke, K., Ehrenschwender, M., Schley, G., et al. (2015) · Cell Reports

Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment

Cited by 110

Role of fibroblast growth factor signalling in hepatic fibrosis

Seitz, T., & Hellerbrand, C. (2021) · Liver International

Liver physiology and pathologyFibroblast Growth Factor Research

Cited by 64

Fibroblast Growth Factor 9 is expressed by activated hepatic stellate cells and promotes progression of hepatocellular carcinoma

Seitz, T., Freese, K., Dietrich, P., Thasler, W. E., Bosserhoff, A., & Hellerbrand, C. (2020) · Scientific Reports

Fibroblast Growth Factor ResearchLiver physiology and pathology

Cited by 47