Lindsley, Craig W.

Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

Jeffrey Conn, P., Christopoulos, A., & Lindsley, C. W. (2009) · Nature Reviews Drug Discovery

Receptor Mechanisms and SignalingNeuroscience and Neuropharmacology Research

Cited by 1,063

Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders

Conn, P. J., Jones, C. K., & Lindsley, C. W. (2009) · Trends in Pharmacological Sciences

Receptor Mechanisms and SignalingNeuroscience and Neuropharmacology Research

Cited by 286

Targeting phospholipase D in cancer, infection and neurodegenerative disorders

Brown, H. A., Thomas, P. G., & Lindsley, C. W. (2017) · Nature Reviews Drug Discovery

Protein Kinase Regulation and GTPase SignalingSphingolipid Metabolism and Signaling

Cited by 209

High-Affinity Small-Molecule Inhibitors of the Menin-Mixed Lineage Leukemia (MLL) Interaction Closely Mimic a Natural Protein–Protein Interaction

He, S., Senter, T. J., Pollock, J., Han, C., Upadhyay, S. K., Purohit, T., Gogliotti, R. D., Lindsley, C. W., Cierpicki, T., Stauffer, S. R., et al. (2014) · Journal of Medicinal Chemistry

Protein Degradation and InhibitorsComputational Drug Discovery Methods

Cited by 99

Allosteric modulation of Class C GPCRs: a novel approach for the treatment of CNS disorders

Engers, D. W., & Lindsley, C. W. (2013) · Drug Discovery Today: Technologies

Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling

Cited by 45

Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics

Vuckovic, Z., Wang, J., Pham, V., Mobbs, J. I., Belousoff, M. J., Bhattarai, A., Burger, W. A., Thompson, G., Yeasmin, M., Nawaratne, V., et al. (2023) · eLife

Receptor Mechanisms and SignalingNeuroscience and Neuropharmacology Research

Cited by 34