Kozany, Christian

A Disulfide Relay System in the Intermembrane Space of Mitochondria that Mediates Protein Import

Mesecke, N., Terziyska, N., Kozany, C., Baumann, F., Neupert, W., Hell, K., & Herrmann, J. M. (2005) · Cell

Mitochondrial Function and PathologyRedox biology and oxidative stress

Cited by 557

Selective inhibitors of the FK506-binding protein 51 by induced fit

Gaali, S., Kirschner, A., Cuboni, S., Hartmann, J., Kozany, C., Balsevich, G., Namendorf, C., Fernandez-Vizarra, P., Sippel, C., Zannas, A. S., et al. (2015) · Nature Chemical Biology

Signaling Pathways in DiseaseTreatment of Major Depression

Cited by 245

Large FK506-binding proteins shape the pharmacology of rapamycin

März, A. M., Fabian, A.-K., Kozany, C., Bracher, A., & Hausch, F. (2013) · Molecular and Cellular Biology

PI3K/AKT/mTOR signaling in cancerSignaling Pathways in Disease

Cited by 141

Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties

Hartmann, J., Wagner, K. V., Gaali, S., Kirschner, A., Kozany, C., Ruhter, G., Dedic, N., Hausl, A. S., Hoeijmakers, L., Westerholz, S., et al. (2015) · Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorStress Responses and Cortisol

Cited by 109

Fluorescent Probes to Characterise FK506‐Binding Proteins

Kozany, C., März, A., Kress, C., & Hausch, F. (2009) · ChemBioChem

Signaling Pathways in DiseasePI3K/AKT/mTOR signaling in cancer

Cited by 91

Evaluation of synthetic FK506 analogues as ligands for the FK506-binding proteins 51 and 52

Gopalakrishnan, R., Kozany, C., Gaali, S., Kress, C., Hoogeland, B., Bracher, A., & Hausch, F. (2012) · Journal of Medicinal Chemistry

Signaling Pathways in DiseasePI3K/AKT/mTOR signaling in cancer

Cited by 64

Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90

Bracher, A., Kozany, C., Thost, A.-K., & Hausch, F. (2011) · Acta Crystallographica Section D Biological Crystallography

Signaling Pathways in DiseaseHeat shock proteins research

Cited by 62

Increasing the efficiency of ligands for FK506-binding protein 51 by conformational control

Wang, Y., Kirschner, A., Fabian, A.-K., Gopalakrishnan, R., Kress, C., Hoogeland, B., Koch, U., Kozany, C., Bracher, A., & Hausch, F. (2013) · Journal of Medicinal Chemistry

Signaling Pathways in DiseaseChemical Synthesis and Analysis

Cited by 60

Exploration of pipecolate sulfonamides as binders of the FK506-binding proteins 51 and 52

Gopalakrishnan, R., Kozany, C., Wang, Y., Schneider, S., Hoogeland, B., Bracher, A., & Hausch, F. (2012) · Journal of Medicinal Chemistry

Chemical Synthesis and AnalysisSignaling Pathways in Disease

Cited by 52

Crystal structures of the free and ligand-bound FK1–FK2 domain segment of FKBP52 reveal a flexible inter-domain hinge

Bracher, A., Kozany, C., Hähle, A., Wild, P., Zacharias, M., & Hausch, F. (2013) · Journal of Molecular Biology

Signaling Pathways in DiseaseHeat shock proteins research

Cited by 45