A Disulfide Relay System in the Intermembrane Space of Mitochondria that Mediates Protein Import

Cell Biology: a Laboratory Handbook

Harris, A. (1995) · Journal of Medical Genetics · doi:10.1136/jmg.32.9.759 · Cited by 1,230 · see citing works

Cell biology :a laboratory handbook.

Celis, J. E. (1994) · Cited by 1,199 · see citing works

Formation and transfer of disulphide bonds in living cells

Sevier, C. S., & Kaiser, C. A. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm954 · Cited by 797 · see citing works

Protein Disulfide Bond Formation in Prokaryotes

Kadokura, H., Katzen, F., & Beckwith, J. (2003) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.72.121801.161459 · Cited by 541 · see citing works

Versatility of the mitochondrial protein import machinery

Pfanner, N., & Geissler, A. (2001) · Nature reviews. Molecular cell biology · doi:10.1038/35073006 · Cited by 521 · see citing works

Characterization of , a Yeast Gene Involved in Copper Metabolism and Assembly of Cytochrome Oxidase

Glerum, D. M., Shtanko, A., & Tzagoloff, A. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.24.14504 · Cited by 496 · see citing works

The ERO1 Gene of Yeast Is Required for Oxidation of Protein Dithiols in the Endoplasmic Reticulum

Frand, A. R., & Kaiser, C. A. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80017-9 · Cited by 495 · see citing works

Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins

Chacińska, A., Pfannschmidt, S., Wiedemann, N., Kozjak‐Pavlovic, V., Szklarz, L. K. S., Schulze‐Specking, A., Truscott, K. N., Guiard, B., Meisinger, C., & Pfanner, N. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600389 · Cited by 464 · see citing works

Cytochromes c1 and b2 are sorted to the intermembrane space of yeast mitochondria by a stop-transfer mechanism

Glick, B. S., Brandt, A., Cunningham, K. W., et al. (1992) · Cell · doi:10.1016/0092-8674(92)90292-k · Cited by 426 · see citing works

Monitoring disulfide bond formation in the eukaryotic cytosol

Østergaard, H., Tachibana, C., & Winther, J. R. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200402120 · Cited by 333 · see citing works

Import of Mitochondrial Carriers Mediated by Essential Proteins of the Intermembrane Space

Koehler, C. M., Jarosch, E., Tokatlidis, K., Schmid, K., Schweyen, R. J., & Schatz, G. (1998) · Science · doi:10.1126/science.279.5349.369 · Cited by 326 · see citing works

New developments in mitochondrial assembly.

Koehler, C. (2004) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.20.010403.105057 · Cited by 307 · see citing works

Carrier protein import into mitochondria mediated by the intermembrane proteins Tim10/Mrs11 and Tim12/Mrs5

Sirrenberg, C., Endres, M., Fölsch, H., Stuart, R. A., Neupert, W., & Brunner, M. (1998) · Nature · doi:10.1038/36136 · Cited by 299 · see citing works

Heterodimeric structure of superoxide dismutase in complex with its metallochaperone.

Lamb, A. L., Torres, A. S., O’Halloran, T. V., & Rosenzweig, A. C. (2001) · Nature Structural Biology · doi:10.1038/nsb0901-751 · Cited by 284 · see citing works

Successive translocation into and out of the mitochondrial matrix: Targeting of proteins to the intermembrane space by a bipartite signal peptide

Hartl, F. U., Ostermann, J., Guiard, B., & Neupert, W. (1987) · Cell · doi:10.1016/0092-8674(87)90589-7 · Cited by 277 · see citing works

Structure of a water soluble fragment of the ‘Rieske’ iron–sulfur protein of the bovine heart mitochondrial cytochrome bc1 complex determined by MAD phasing at 1.5 å resolution

Iwata, S., Saynovits, M., Link, T. A., et al. (1996) · Structure · doi:10.1016/s0969-2126(96)00062-7 · Cited by 273 · see citing works

An essential function of the mitochondrial sulfhydryl oxidase Erv1p/ALR in the maturation of cytosolic Fe/S proteins

Lange, H., Lisowsky, T., Gerber, J., Mühlenhoff, U., Kispál, G., & Lill, R. (2001) · EMBO Reports · doi:10.1093/embo-reports/kve161 · Cited by 269 · see citing works

Factors Controlling the Uptake of Yeast Copper/Zinc Superoxide Dismutase into Mitochondria

Field, L. S., Furukawa, Y., O’Halloran, T. V., & Culotta, V. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m304296200 · Cited by 230 · see citing works

The Tim9p–Tim10p complex binds to the transmembrane domains of the ADP/ATP carrier

Curran, S. P., Leuenberger, D., Oppliger, W., & Koehler, C. M. (2002) · The EMBO Journal · doi:10.1093/emboj/21.5.942 · Cited by 220 · see citing works

Oxidative protein folding in bacteria

Collet, J., & Bardwell, J. C. A. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.02851.x · Cited by 213 · see citing works

Identification of Tim40 That Mediates Protein Sorting to the Mitochondrial Intermembrane Space

Naoé, M., Ohwa, Y., Ishikawa, D., Ohshima, C., Nishikawa, S., Yamamoto, H., & Endo, T. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m410272200 · Cited by 207 · see citing works

A new FAD-binding fold and intersubunit disulfide shuttle in the thiol oxidase Erv2p

Gross, E., Sevier, C. S., Vala, A., Kaiser, C. A., & Fass, D. (2001) · Nature Structural Biology · doi:10.1038/nsb740 · Cited by 181 · see citing works

A flavoprotein oxidase defines a new endoplasmic reticulum pathway for biosynthetic disulphide bond formation

Sevier, C. S., Cuozzo, J. W., Vala, A., Åslund, F., & Kaiser, C. A. (2001) · Nature Cell Biology · doi:10.1038/ncb1001-874 · Cited by 178 · see citing works

Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions

Terziyska, N., Lutz, T., Kozany, C., Mokranjac, D., Mesecke, N., Neupert, W., Herrmann, J. M., & Hell, K. (2004) · FEBS Letters · doi:10.1016/j.febslet.2004.11.072 · Cited by 173 · see citing works

Erv1p from Saccharomyces cerevisiae is a FAD‐linked sulfhydryl oxidase

Lee, J.-E., Hofhaus, G., & Lisowsky, T. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)01767-1 · Cited by 167 · see citing works

The small Tim proteins and the twin Cx3C motif

Koehler, C. M. (2003) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2003.11.003 · Cited by 139 · see citing works

Functions of outer membrane receptors in mitochondrial protein import.

Endo, T., & Kohda, D. (2002) · Biochimica et Biophysica Acta · doi:10.1016/s0167-4889(02)00259-8 · Cited by 133 · see citing works

Import of small Tim proteins into the mitochondrial intermembrane space

Lutz, T., Neupert, W., & Herrmann, J. M. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg421 · Cited by 128 · see citing works

Protein import into and across the mitochondrial inner membrane: role of the TIM23 and TIM22 translocons

Jensen, R. E., & Dunn, C. D. (2002) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(02)00261-6 · Cited by 125 · see citing works

Functional TIM10 Chaperone Assembly Is Redox-regulated in Vivo

Lu, H., Allen, S. P., Wardleworth, L., Savory, P., & Tokatlidis, K. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m313045200 · Cited by 120 · see citing works

Dual function of a new nuclear gene for oxidative phosphorylation and vegetative growth in yeast

Lisowsky, T. (1992) · Molecular and General Genetics MGG · doi:10.1007/bf00299137 · Cited by 117 · see citing works

Chopped, trapped or tacked – protein translocation into the IMS of mitochondria

Herrmann, J. M., & Hell, K. (2005) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2005.02.005 · Cited by 113 · see citing works

Crystal Structure of Human SCO1

Williams, J. C., Sue, C. M., Banting, G. S., Yang, H., Glerum, D. M., Hendrickson, W. A., & Schon, E. A. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m410705200 · Cited by 112 · see citing works

Mutational Analysis of the Mitochondrial Copper Metallochaperone Cox17

Heaton, D. N., Nittis, T., Srinivasan, C., & Winge, D. R. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m006639200 · Cited by 108 · see citing works

Yeast Erv2p Is the First Microsomal FAD-linked Sulfhydryl Oxidase of the Erv1p/Alrp Protein Family

Gerber, J., Mühlenhoff, U., Hofhaus, G., Lill, R., & Lisowsky, T. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m100134200 · Cited by 106 · see citing works

Solution Structure of Cox11, a Novel Type of β-Immunoglobulin-like Fold Involved in CuB Site Formation of Cytochrome c Oxidase

Banci, L., Bertini, I., Cantini, F., Ciofi‐Baffoni, S., Gonnelli, L., & Mangani, S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m403655200 · Cited by 100 · see citing works

The Role of Hot13p and Redox Chemistry in the Mitochondrial TIM22 Import Pathway

Curran, S. P., Leuenberger, D., Leverich, E. P., Hwang, D. K., Beverly, K. N., & Koehler, C. M. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m404878200 · Cited by 87 · see citing works

Unique Features of Plant Mitochondrial Sulfhydryl Oxidase

Levitan, A., Danon, A., & Lisowsky, T. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312877200 · Cited by 77 · see citing works

Isolation of yeast mitochondria and study of mitochondrial protein translation

Herrmann, J. M., Fölsch, H., Neupert, W., et al. (1994) · Open access LMU (Ludwid Maxmilian's Universitat Munchen) · doi:10.5282/ubm/epub.7675 · Cited by 75 · see citing works

Analysis of protein-protein interactions in mitochondria by coimmunoprecipitation and chemical cross-linking

Herrmann, J. M., Westermann, B., & Neupert, W. (2001) · Methods in cell biology · doi:10.1016/s0091-679x(01)65013-1 · Cited by 32 · see citing works

Disulfide relays between and within proteins: the Ero1p structure

Hiniker, A. O., & Bardwell, J. C. A. (2004) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2004.08.002 · Cited by 14 · see citing works

Deletion of six open reading frames from the left arm of chromosome IV of Saccharomyces cerevisiae

Tuller, G., Prein, B., Jandrositz, A., Daum, G., & Kohlwein, S. D. (1999) · Yeast · doi:10.1002/(sici)1097-0061(19990915)15:12 · Cited by 8 · see citing works

Function and biogenesis of iron-sulphur proteins

Lill, R. (2009) · Nature · doi:10.1038/nature08301 · Cited by 1,167 · see citing works

Mitochondrial protein import: from proteomics to functional mechanisms

Schmidt, O., Pfanner, N., & Meisinger, C. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2959 · Cited by 717 · see citing works

Redox regulation of mitochondrial function

Handy, D. E., & Loscalzo, J. (2012) · Antioxidants & Redox Signaling · doi:10.1089/ars.2011.4123 · Cited by 588 · see citing works

Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease

Lane, D. J. R., Merlot, A. M., Huang, M. L.-H., Bae, D.-H., Jansson, P. J., Sahni, S., Kalinowski, D. S., & Richardson, D. R. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2015.01.021 · Cited by 399 · see citing works

Iron-Sulfur Protein Biogenesis in Eukaryotes: Components and Mechanisms

Lill, R., & Mühlenhoff, U. (2006) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.22.010305.104538 · Cited by 365 · see citing works

Chemistry and Enzymology of Disulfide Cross-Linking in Proteins

Fass, D., & Thorpe, C. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00123 · Cited by 321 · see citing works

Mitochondrial copper metabolism and delivery to cytochrome <i>c</i> oxidase

Horn, D., & Barrientos, A. (2008) · IUBMB Life · doi:10.1002/iub.50 · Cited by 283 · see citing works

The Redox Environment in the Mitochondrial Intermembrane Space Is Maintained Separately from the Cytosol and Matrix

Hu, J., Dong, L., & Outten, C. E. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m803028200 · Cited by 273 · see citing works

The redox proteome

Go, Y.-M., & Jones, D. P. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.r113.464131 · Cited by 260 · see citing works

Erv1 Mediates the Mia40-dependent Protein Import Pathway and Provides a Functional Link to the Respiratory Chain by Shuttling Electrons to Cytochrome c

Allen, S., Balabanidou, V., Sideris, D. P., Lisowsky, T., & Tokatlidis, K. (2005) · Journal of Molecular Biology · doi:10.1016/j.jmb.2005.08.049 · Cited by 235 · see citing works

Mitochondrial Disulfide Bond Formation Is Driven by Intersubunit Electron Transfer in Erv1 and Proofread by Glutathione

Bien, M., Longen, S., Wagener, N., Chwalla, I., Herrmann, J. M., & Riemer, J. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.01.017 · Cited by 179 · see citing works

The Saccharomyces cerevisiae Proteome of Oxidized Protein Thiols

Le Moan, N., Clement, G., Le Maout, S., Tacnet, F., & Toledano, M. B. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m513346200 · Cited by 170 · see citing works

The Ubiquitin-Proteasome System Regulates Mitochondrial Intermembrane Space Proteins

Bragoszewski, P., Gornicka, A., Sztolsztener, M. E., & Chacinska, A. (2013) · Molecular and Cellular Biology · doi:10.1128/mcb.01579-12 · Cited by 149 · see citing works

A role for cytochrome c and cytochrome c peroxidase in electron shuttling from Erv1

Dabir, D. V., Leverich, E. P., Kim, S., Tsai, F. D., Hirasawa, M., Knaff, D. B., & Koehler, C. M. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601909 · Cited by 162 · see citing works

The Mitochondrial Disulfide Relay System Protein GFER Is Mutated in Autosomal-Recessive Myopathy with Cataract and Combined Respiratory-Chain Deficiency

Di Fonzo, A., Ronchi, D., Lodi, T., Fassone, E., Tigano, M., Lamperti, C., Corti, S., Bordoni, A., Fortunato, F., Nizzardo, M., et al. (2009) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2009.04.004 · Cited by 141 · see citing works

Repurposing Approach Identifies Auranofin with Broad Spectrum Antifungal Activity That Targets Mia40-Erv1 Pathway

Thangamani, S., Maland, M., Mohammad, H., Pascuzzi, P. E., Avramova, L., Koehler, C. M., Hazbun, T. R., & Seleem, M. N. (2017) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2017.00004 · Cited by 90 · see citing works

Oxidation-driven protein import into mitochondria: Insights and blind spots

Riemer, J., Fischer, M., & Herrmann, J. M. (2011) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2010.06.003 · Cited by 58 · see citing works

Trapping Oxidative Folding Intermediates During Translocation to the Intermembrane Space of Mitochondria: In Vivo and In Vitro Studies

Sideris, D. P., & Tokatlidis, K. (2010) · Methods in Molecular Biology · doi:10.1007/978-1-60327-412-8_25 · Cited by 8 · see citing works

Identification of the Signal Directing Tim9 and Tim10 into the Intermembrane Space of Mitochondria

Milenkovic, D., Ramming, T., Müller, J. M., Wenz, L.-S., Gebert, N., Schulze‐Specking, A., Stojanovski, D., Rospert, S., & Chacińska, A. (2009) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-11-1108 · Cited by 167 · see citing works

Precursor Oxidation by Mia40 and Erv1 Promotes Vectorial Transport of Proteins into the Mitochondrial Intermembrane Space

Müller, J. M., Milenkovic, D., Guiard, B., Pfanner, N., & Chacińska, A. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-08-0814 · Cited by 79 · see citing works

Redox activation of mitochondrial intermembrane space Cu,Zn-superoxide dismutase

Iñarrea, P., Moini, H., Rettori, D., Han, D., MARTÍNEZ, J., García‐Rubio, I., Fernández‐Vizarra, E., Iturralde, M., & Cadenas, E. (2005) · Biochemical Journal · doi:10.1042/bj20041683 · Cited by 59 · see citing works

The role of adenylate kinase in dynamic compartmentation of adenine nucleotides in the mitochondrial intermembrane space

Gellerich, F. N. (1992) · FEBS Letters · doi:10.1016/0014-5793(92)80326-c · Cited by 61 · see citing works

The MIA system for protein import into the mitochondrial intermembrane space

Stojanovski, D., Müller, J. M., Milenkovic, D., Guiard, B., Pfanner, N., & Chacińska, A. (2007) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2007.10.004 · Cited by 76 · see citing works