Takegami, Yujiro

CRISPR-Cas9–mediated gene knockout in intestinal tumor organoids provides functional validation for colorectal cancer driver genes

Takeda, H., Kataoka, S., Nakayama, M., Ali, M. A. E., Oshima, H., Yamamoto, D., Park, J.-W., Takegami, Y., An, T., Jenkins, N. A., et al. (2019) · Proceedings of the National Academy of Sciences

CRISPR and Genetic EngineeringGenetic factors in colorectal cancer

Cited by 172

RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity

Muraguchi, T., Takegami, Y., Ohtsuka, T., Kitajima, S., Chandana, E. P. S., Omura, A., Miki, T., Takahashi, R., Matsumoto, N., Ludwig, A., et al. (2007) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 149

Rb Regulates DNA Damage Response and Cellular Senescence through E2F-Dependent Suppression of N-Ras Isoprenylation

Shamma, A., Takegami, Y., Miki, T., Kitajima, S., Noda, M., Obara, T., Okamoto, T., & Takahashi, C. (2009) · Cancer Cell

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 140

PD-1 Imposes Qualitative Control of Cellular Transcriptomes in Response to T Cell Activation

Shimizu, K., Sugiura, D., Okazaki, I.-M., Maruhashi, T., Takegami, Y., Cheng, C., Ozaki, S., & Okazaki, T. (2020) · Molecular Cell

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 63