Sembrat, John

PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis

Bueno, M., Lai, Y.-C., Romero, Y., Brands, J., St. Croix, C. M., Kamga, C., Corey, C., Herazo-Maya, J. D., Sembrat, J., Lee, J. S., et al. (2015) · Journal of Clinical Investigation

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisMitochondrial Function and Pathology

Cited by 627

IPF lung fibroblasts have a senescent phenotype

Álvarez, D., Cárdenes, N., Sellarés, J., Bueno, M., Corey, C., Hanumanthu, V. S., Peng, Y., D’Cunha, H., Sembrat, J., Nouraie, M., et al. (2017) · American Journal of Physiology-Lung Cellular and Molecular Physiology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTelomeres, Telomerase, and Senescence

Cited by 342

NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health.

SenNet Consortium, Writing Group, Lee, P. J., Benz, C. C., Blood, P., Börner, K., Campisi, J., Chen, F., Daldrup-Link, H., De Jager, P., et al. (2022) · Nature Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 122

Unagi: Deep Generative Model for Deciphering Cellular Dynamics and In-Silico Drug Discovery in Complex Diseases

Zheng, Y., Schupp, J., Adams, T., Clair, G., Justet, A., Ahangari, F., Yan, X., Hansen, P., Carlon, M., Cortesi, E., et al. (2023) · Nature Biomedical Engineering

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 34

Non-Canonical TERT Activity Initiates Osteogenesis in Calcific Aortic Valve Disease

Cuevas, R. A., Hortells, L., Chu, C. C., Wong, R., Crane, A., Boufford, C. K., Regan, C., Moorhead, W. J., Bashline, M. J., Parwal, A., et al. (2025) · Circulation Research

Cardiac Valve Diseases and TreatmentsTelomeres, Telomerase, and Senescence

Cited by 11