Sidoli, Simone

An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer’s disease

Nativio, R., Lan, Y., Donahue, G., Sidoli, S., Berson, A., Srinivasan, A. R., Shcherbakova, O., Amlie-Wolf, A., Nie, J., Cui, X., et al. (2020) · Nature Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 380

Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis

Carrer, A., Trefely, S., Zhao, S., Campbell, S. L., Norgard, R. J., Schultz, K. C., Sidoli, S., Parris, J. L. D., Affronti, H. C., Sivanand, S., et al. (2019) · Cancer Discovery

Cancer, Lipids, and MetabolismPancreatic and Hepatic Oncology Research

Cited by 313

Transcription Factor Cooperativity in Early Adipogenic Hotspots and Super-Enhancers

Siersbæk, R., Rabiee, A., Nielsen, R., Sidoli, S., Traynor, S., Loft, A., Poulsen, L. L. C., Rogowska-Wrzesinska, A., Jensen, O. N., & Mandrup, S. (2014) · Cell Reports

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 234

Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence

Sen, P., Lan, Y., Li, C. Y., Sidoli, S., Donahue, G., Dou, Z., Frederick, B., Chen, Q., Luense, L. J., Garcia, B. A., et al. (2019) · Molecular Cell

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 164

Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons

Kronman, H., Torres-Berrío, A., Sidoli, S., Issler, O., Godino, A., Ramakrishnan, A., Mews, P., Lardner, C. K., Parise, E. M., Walker, D. M., et al. (2021) · Nature Neuroscience

Stress Responses and CortisolEpigenetics and DNA Methylation

Cited by 108

Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model

Carling, G. K., Fan, L., Foxe, N. R., Norman, K., Wong, M. Y., Zhu, D., Corona, C., Razzoli, A., Yu, F., Yarahmady, A., et al. (2024) · Neuron

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 89

Middle‐down hybrid chromatography/tandem mass spectrometry workflow for characterization of combinatorial post‐translational modifications in histones

Sidoli, S., Schwämmle, V., Ruminowicz, C., Hansen, T. A., Wu, X., Helin, K., & Jensen, O. N. (2014) · PROTEOMICS

Advanced Proteomics Techniques and ApplicationsGenomics and Chromatin Dynamics

Cited by 87

An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides

Armour, S. M., Remsberg, J. R., Damle, M., Sidoli, S., Ho, W. Y., Li, Z., Garcia, B. A., & Lazar, M. A. (2017) · Nature Communications

Histone Deacetylase Inhibitors ResearchLiver Disease Diagnosis and Treatment

Cited by 69

Bottom-Up and Middle-Down Proteomics Have Comparable Accuracies in Defining Histone Post-Translational Modification Relative Abundance and Stoichiometry

Sidoli, S., Lin, S., Karch, K. R., & Garcia, B. A. (2015) · Analytical Chemistry

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 67

Analyses of Histone Proteoforms Using Front-end Electron Transfer Dissociation-enabled Orbitrap Instruments

Anderson, L. C., Karch, K. R., Ugrin, S. A., Coradin, M., English, A. M., Sidoli, S., Shabanowitz, J., Garcia, B. A., & Hunt, D. F. (2016) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 60

DPP4 inhibition impairs senohemostasis to improve plaque stability in atherosclerotic mice

Herman, A. B., Tsitsipatis, D., Anerillas, C., Mazan-Mamczarz, K., Carr, A. E., Gregg, J. M., Wang, M., Zhang, J., Michel, M., Henry-Smith, C. A., et al. (2023) · Journal of Clinical Investigation

Telomeres, Telomerase, and SenescenceAtherosclerosis and Cardiovascular Diseases

Cited by 50

Reduced endosomal microautophagy activity in aging associates with enhanced exocyst‐mediated protein secretion

Krause, G. J., Diaz, A., Jafari, M., Khawaja, R. R., Agullo‐Pascual, E., Santiago‐Fernández, O., Richards, A. L., Chen, K., Dmitriev, P., Sun, Y., et al. (2022) · Aging Cell

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 35