Muckenthaler, Martina U.

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

Thum, T., Gross, C., Fiedler, J., Fischer, T., Kissler, S., Bussen, M., Galuppo, P., Just, S., Rottbauer, W., Frantz, S., et al. (2008) · Nature

Cardiac Fibrosis and RemodelingMicroRNA in disease regulation

Cited by 2,349

Two to tango: Regulation of Mammalian iron metabolism

Hentze, M. W., Muckenthaler, M. U., Galy, B., & Camaschella, C. (2010) · Cell

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 2,120

Balancing Acts

Hentze, M. W., Muckenthaler, M. U., & Andrews, N. C. (2004) · Cell

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 1,736

A Red carpet for iron metabolism

Muckenthaler, M. U., Rivella, S., Hentze, M. W., & Galy, B. (2017) · Cell

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 1,319

Iron deficiency

Pasricha, S.-R., Tye-Din, J., Muckenthaler, M. U., & Swinkels, D. W. (2021) · The Lancet

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 1,069

Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network

Muckenthaler, M. U., Galy, B., & Hentze, M. W. (2008) · Annual Review of Nutrition

Iron Metabolism and DisordersTrace Elements in Health

Cited by 701

STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation

Verga Falzacappa, M. V., Vujic Spasic, M., Kessler, R., Stolte, J., Hentze, M. W., & Muckenthaler, M. U. (2007) · Blood

Iron Metabolism and DisordersCytokine Signaling Pathways and Interactions

Cited by 567

Iron Toxicity in Diseases of Aging: Alzheimer's Disease, Parkinson's Disease and Atherosclerosis

Altamura, S., & Muckenthaler, M. U. (2009) · Journal of Alzheimer's Disease

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 369

IRP-1 binding to ferritin mRNA prevents the recruitment of the small ribosomal subunit by the cap-binding complex eIF4F.

Muckenthaler, M., Gray, N. K., & Hentze, M. W. (1998) · Molecular Cell

RNA and protein synthesis mechanismsIron Metabolism and Disorders

Cited by 297

Heme controls ferroportin1 (FPN1) transcription involving Bach1, Nrf2 and a MARE/ARE sequence motif at position -7007 of the FPN1 promoter

Marro, S., Chiabrando, D., Messana, E., Stolte, J., Turco, E., Tolosano, E., & Muckenthaler, M. U. (2010) · Haematologica

Iron Metabolism and DisordersHeme Oxygenase-1 and Carbon Monoxide

Cited by 297

Iron-regulatory proteins limit hypoxia-inducible factor-2α expression in iron deficiency

Sanchez, M., Galy, B., Muckenthaler, M. U., & Hentze, M. W. (2007) · Nature Structural & Molecular Biology

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 294

Hemopexin therapy reverts heme-induced proinflammatory phenotypic switching of macrophages in a mouse model of sickle cell disease

Vinchi, F., Costa da Silva, M., Ingoglia, G., Petrillo, S., Brinkman, N., Zuercher, A., Cerwenka, A., Tolosano, E., & Muckenthaler, M. U. (2016) · Blood

Hemoglobinopathies and Related DisordersHemoglobin structure and function

Cited by 269

Nitric oxide–mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection

Nairz, M., Schleicher, U., Schroll, A., Sonnweber, T., Theurl, I., Ludwiczek, S., Talasz, H., Brandacher, G., Moser, P. L., Muckenthaler, M. U., et al. (2013) · Journal of Experimental Medicine

Iron Metabolism and DisordersImmune Response and Inflammation

Cited by 204

The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation

D’Alessio, F., Hentze, M. W., & Muckenthaler, M. U. (2012) · Journal of Hepatology

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 200

Identification of Cholesterol-Regulating Genes by Targeted RNAi Screening

Bartz, F., Kern, L., Erz, D., Zhu, M., Gilbert, D., Meinhof, T., Wirkner, U., Erfle, H., Muckenthaler, M., Pepperkok, R., et al. (2009) · Cell Metabolism

Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism

Cited by 198

Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells

Guo, W., Bachman, E., Li, M., Roy, C. N., Blusztajn, J., Wong, S., Chan, S. Y., Serra, C., Jasuja, R., Travison, T. G., et al. (2013) · Aging Cell

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 192

A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia

Guida, C., Altamura, S., Klein, F. A., Galy, B., Boutros, M., Ulmer, A. J., Hentze, M. W., & Muckenthaler, M. U. (2015) · Blood

Iron Metabolism and DisordersImmune Response and Inflammation

Cited by 173

Iron induces anti-tumor activity in tumor-associated macrophages

Costa da Silva, M., Breckwoldt, M. O., Vinchi, F., Correia, M. P., Stojanovic, A., Thielmann, C. M., Meister, M., Muley, T., Warth, A., Platten, M., et al. (2017) · Frontiers in Immunology

Immune cells in cancerBacterial Cancer Therapy

Cited by 164

Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD

Casanovas, G., Mleczko-Sanecka, K., Altamura, S., Hentze, M. W., & Muckenthaler, M. U. (2009) · Journal of Molecular Medicine

Iron Metabolism and DisordersTGF-β signaling in diseases

Cited by 161

Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1

Ludwiczek, S., Theurl, I., Muckenthaler, M. U., Jakab, M., Mair, S. M., Theurl, M., Kiss, J., Paulmichl, M., Hentze, M. W., Ritter, M., et al. (2007) · Nature Medicine

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 160

A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells

Verga Falzacappa, M. V., Casanovas, G., Hentze, M. W., & Muckenthaler, M. U. (2008) · Journal of Molecular Medicine

Iron Metabolism and DisordersPlant Micronutrient Interactions and Effects

Cited by 146

Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB

Sonnweber, T., Nachbaur, D., Schroll, A., Nairz, M., Seifert, M., Demetz, E., Haschka, D., Mitterstiller, A.-M., Kleinsasser, A., Burtscher, M., et al. (2014) · Gut

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 145

Poly(A)-tail-promoted translation in yeast: Implications for translational control

PREISS, T., MUCKENTHALER, M., & HENTZE, M. W. (1998) · RNA

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 123

Resistance of ferroportin to hepcidin binding causes exocrine pancreatic failure and fatal iron overload

Altamura, S., Kessler, R., Gröne, H.-J., Gretz, N., Hentze, M. W., Galy, B., & Muckenthaler, M. U. (2014) · Cell Metabolism

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 119