Heesom, Kate J.

Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein

Davidson, A. D., Williamson, M. K., Lewis, S., Shoemark, D., Carroll, M. W., Heesom, K. J., Zambon, M., Ellis, J., Lewis, P. A., Hiscox, J. A., et al. (2020) · Genome Medicine

SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies

Cited by 457

The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes

Berwick, D. C., Hers, I., Heesom, K. J., Moule, S. K., & Tavareá, J. M. (2002) · Journal of Biological Chemistry

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 383

Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling

McNally, K. E., Faulkner, R., Steinberg, F., Gallon, M., Ghai, R., Pim, D., Langton, P., Pearson, N., Danson, C. M., Nägele, H., et al. (2017) · Nature Cell Biology

Cellular transport and secretionAutophagy in Disease and Therapy

Cited by 346

SNX17 protects integrins from degradation by sorting between lysosomal and recycling pathways

Steinberg, F., Heesom, K. J., Bass, M. D., & Cullen, P. J. (2012) · Journal of Cell Biology

Cellular transport and secretionCell Adhesion Molecules Research

Cited by 206

De novo derivation of proteomes from transcriptomes for transcript and protein identification

Evans, V. C., Barker, G., Heesom, K. J., Fan, J., Bessant, C., & Matthews, D. A. (2012) · Nature Methods

Advanced Proteomics Techniques and ApplicationsGenomics and Phylogenetic Studies

Cited by 166

Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome

Healy, M. D., McNally, K. E., Butkovič, R., Chilton, M., Kato, K., Sacharz, J., McConville, C., Moody, E. R. R., Shaw, S., Planelles-Herrero, V. J., et al. (2023) · Cell

Cellular transport and secretionAutophagy in Disease and Therapy

Cited by 91

Dysregulation of Mesenchymal Stromal Cell Antioxidant Responses in Progressive Multiple Sclerosis

Redondo, J., Sarkar, P., Kemp, K., Heesom, K. J., Wilkins, A., Scolding, N. J., & Rice, C. M. (2018) · Stem Cells Translational Medicine

Mesenchymal stem cell researchMultiple Sclerosis Research Studies

Cited by 37

Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27–Retromer complex

Guo, Q., Chen, K.-E., Gimenez-Andres, M., Jellett, A. P., Gao, Y., Simonetti, B., Liu, M., Danson, C. M., Heesom, K. J., Cullen, P. J., et al. (2024) · Proceedings of the National Academy of Sciences

Cellular transport and secretionMicrotubule and mitosis dynamics

Cited by 19

Mapping the endosomal proximity proteome reveals Retromer as a hub for RAB GTPase regulation

Antón-Plágaro, C., Chen, K.-E., Guo, Q., Liu, M., Evans, A. J., Lewis, P. A., Heesom, K. J., Wilkinson, K. A., Collins, B. M., & Cullen, P. J. (2024) · Nature Communications

Cellular transport and secretionAutophagy in Disease and Therapy

Cited by 14

Mapping of endosomal proximity proteomes reveals Retromer as a hub for RAB GTPase regulation

Antón-Plágaro, C., Chen, K.-E., Guo, Q., Liu, M., Evans, A. J., Lewis, P. A., Heesom, K. J., Wilkinson, K. A., Collins, B. M., & Cullen, P. J. (2025) · Nature Communications

Cellular transport and secretionAutophagy in Disease and Therapy

Cited by 14

Ritscher-Schinzel syndrome can be characterized as an endosomal recyclinopathy

Kato, K., Nishio, Y., McMillan, K. J., Al-Maraghi, A., Kroes, H. Y., Abdel-Hamid, M. S., Jones, E., Shaw, S., Yoshida, A., Otsuji, S., et al. (2025) · Science Translational Medicine

Cellular transport and secretionGenomics and Rare Diseases

Cited by 7

DNAAF9 (Shulin) and ARL3 regulate the transport and activation of ciliary Outer Dynein Arms (ODAs)

Issa, K. H. B., Ren, M., Burnet, B., Melia, C., Heesom, K., & Mali, G. R. (2024) · Nature Structural & Molecular Biology

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 6

Molecular basis for the activation of outer dynein arms in cilia

Issa, K. H. B., Ren, M., Burnet, B., Lu, H., Melia, C., Heesom, K., Roberts, A. J., Roy, S., & Mali, G. R. (2025) · Nature Structural & Molecular Biology

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 6

Global identification of neuronal and astrocytic integral membrane proteins that require Retromer for their endosomal recycling

Jones, E., Adams, H., Chen, K.-E., Maroof, F., Ibbotson, T. M., Nakamura, Y., Banks, P. J., Healy, M. D., Lewis, P. A., Heesom, K. J., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory)

Cellular transport and secretionAlzheimer's disease research and treatments

Cited by 0