Sansom, Owen J.
Cancer Research UK Scotland Institute · University of Glasgow
36 papers on CoChatORCID 0000-0001-9540-3010
Most cited papers
- Verified
HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia
Rai, T. S., Cole, J. J., Nelson, D. M., Dikovskaya, D., Faller, W. J., Vizioli, M. G., Hewitt, R. N., Anannya, O., McBryan, T., Manoharan, I., et al. (2014) · Genes & Development
Genomics and Chromatin DynamicsTelomeres, Telomerase, and Senescence
Cited by 162
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Dasatinib Inhibits the Development of Metastases in a Mouse Model of Pancreatic Ductal Adenocarcinoma
Morton, J. P., Karim, S. A., Graham, K., Timpson, P., Jamieson, N., Athineos, D., Doyle, B., McKay, C., Heung, M., Oien, K. A., et al. (2010) · Gastroenterology
Pancreatic and Hepatic Oncology ResearchProtein Kinase Regulation and GTPase Signaling
Cited by 148
- Verified
Luminal iron levels govern intestinal tumorigenesis after Apc loss in vivo
Radulescu, S., Brookes, M. J., Salgueiro, P., Ridgway, R. A., McGhee, E., Anderson, K., Ford, S. J., Stones, D. H., Iqbal, T. H., Tselepis, C., et al. (2012) · Cell Reports
Iron Metabolism and DisordersFerroptosis and cancer prognosis
Cited by 130
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Senescence Sensitivity of Breast Cancer Cells Is Defined by Positive Feedback Loop between CIP2A and E2F1
Laine, A., Sihto, H., Come, C., Rosenfeldt, M. T., Zwolinska, A., Niemelä, M., Khanna, A., Chan, E. K., Kähäri, V.-M., Kellokumpu-Lehtinen, P.-L., et al. (2013) · Cancer Discovery
Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways
Cited by 130
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MNK Inhibition Sensitizes KRAS -Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression
Knight, J. R. P., Alexandrou, C., Skalka, G. L., Vlahov, N., Pennel, K., Officer, L., Teodosio, A., Kanellos, G., Gay, D. M., May-Wilson, S., et al. (2021) · Cancer Discovery
PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling
Cited by 96
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Activation of PP2A and Inhibition of mTOR Synergistically Reduce MYC Signaling and Decrease Tumor Growth in Pancreatic Ductal Adenocarcinoma
Allen-Petersen, B. L., Risom, T., Feng, Z., Wang, Z., Jenny, Z. P., Thoma, M. C., Pelz, K. R., Morton, J. P., Sansom, O. J., Lopez, C. D., et al. (2019) · Cancer Research
PI3K/AKT/mTOR signaling in cancerPancreatic and Hepatic Oncology Research
Cited by 85
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c‐Src drives intestinal regeneration and transformation
Cordero, J. B., Ridgway, R. A., Valeri, N., Nixon, C., Frame, M. C., Muller, W. J., Vidal, M., & Sansom, O. J. (2014) · The EMBO Journal
Protein Kinase Regulation and GTPase SignalingCancer Cells and Metastasis
Cited by 77
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Serine 62-Phosphorylated MYC Associates with Nuclear Lamins and Its Regulation by CIP2A Is Essential for Regenerative Proliferation
Myant, K., Qiao, X., Halonen, T., Come, C., Laine, A., Janghorban, M., Partanen, J. I., Cassidy, J., Ogg, E.-L., Cammareri, P., et al. (2015) · Cell Reports
Cancer-related Molecular PathwaysNuclear Structure and Function
Cited by 59
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BCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancer
Ramesh, P., Lannagan, T. R. M., Jackstadt, R., Atencia Taboada, L., Lansu, N., Wirapati, P., van Hooff, S. R., Dekker, D., Pritchard, J., Kirov, A. B., et al. (2021) · Cell Death & Differentiation
Cell death mechanisms and regulationCancer-related Molecular Pathways
Cited by 52
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The RAC1 Target NCKAP1 Plays a Crucial Role in the Progression of Braf;Pten-Driven Melanoma in Mice
Swaminathan, K., Campbell, A., Papalazarou, V., Jaber-Hijazi, F., Nixon, C., McGhee, E., Strathdee, D., Sansom, O. J., & Machesky, L. M. (2021) · Journal of Investigative Dermatology
Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling
Cited by 18
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Activation of innate-adaptive immune machinery by poly(I:C) exposes a therapeutic vulnerability to prevent relapse in stroma-rich colon cancer
Corry, S. M., McCorry, A. M., Lannagan, T. R., Leonard, N. A., Fisher, N. C., Byrne, R. M., Tsantoulis, P., Cortes-Lavaud, X., Amirkhah, R., Redmond, K. L., et al. (2022) · Gut
Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers
Cited by 18
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Absent expansion of AXIN2+ hepatocytes and altered physiology in Axin2CreERT2 mice challenges the role of pericentral hepatocytes in homeostatic liver regeneration
May, S., Müller, M., Livingstone, C. R., Skalka, G. L., Walsh, P. J., Nixon, C., Hedley, A., Shaw, R., Clark, W., Vande Voorde, J., et al. (2023) · Journal of Hepatology
Liver physiology and pathologyWnt/β-catenin signaling in development and cancer
Cited by 13
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