Ayuso, Eduard

Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer

Bernardes de Jesus, B., Vera, E., Schneeberger, K., Tejera, A. M., Ayuso, E., Bosch, F., & Blasco, M. A. (2012) · EMBO Molecular Medicine

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 548

Whole body correction of mucopolysaccharidosis IIIA by intracerebrospinal fluid gene therapy

Haurigot, V., Marcó, S., Ribera, A., Garcia, M., Ruzo, A., Villacampa, P., Ayuso, E., Añor, S., Andaluz, A., Pineda, M., et al. (2013) · Journal of Clinical Investigation

Lysosomal Storage Disorders ResearchVirus-based gene therapy research

Cited by 215

Pharmacology of Recombinant Adeno-associated Virus Production

Penaud-Budloo, M., François, A., Clément, N., & Ayuso, E. (2018) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchViral Infectious Diseases and Gene Expression in Insects

Cited by 177

Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction

Bär, C., de Jesus, B. B., Serrano, R., Tejera, A., Ayuso, E., Jimenez, V., Formentini, I., Bobadilla, M., Mizrahi, J., de Martino, A., et al. (2014) · Nature Communications

Congenital heart defects researchTelomeres, Telomerase, and Senescence

Cited by 162

Production, purification and characterization of adeno-associated vectors

Ayuso, E., Mingozzi, F., & Bosch, F. (2010) · Current Gene Therapy

Virus-based gene therapy researchViral Infectious Diseases and Gene Expression in Insects

Cited by 151

Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells

Ferrari, S., Jacob, A., Cesana, D., Laugel, M., Beretta, S., Varesi, A., Unali, G., Conti, A., Canarutto, D., Albano, L., et al. (2022) · Cell stem cell

Virus-based gene therapy researchCRISPR and Genetic Engineering

Cited by 133

Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material

Lock, M., McGorray, S., Auricchio, A., Ayuso, E., Beecham, E. J., Blouin-Tavel, V., Bosch, F., Bose, M., Byrne, B. J., Caton, T., et al. (2010) · Human Gene Therapy

Virus-based gene therapy researchViral Infectious Diseases and Gene Expression in Insects

Cited by 131

Manufacturing and characterization of a recombinant adeno-associated virus type 8 reference standard material

Ayuso, E., Blouin, V., Lock, M., McGorray, S., Leon, X., Alvira, M. R., Auricchio, A., Bucher, S., Chtarto, A., Clark, K. R., et al. (2014) · Human Gene Therapy

Virus-based gene therapy researchViral Infectious Diseases and Gene Expression in Insects

Cited by 94

Chemical modification of the adeno-associated virus capsid to improve gene delivery

Mével, M., Bouzelha, M., Leray, A., Pacouret, S., Guilbaud, M., Penaud-Budloo, M., Alvarez-Dorta, D., Dubreil, L., Gouin, S. G., Combal, J. P., et al. (2020) · Chemical Science

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 92

Practical utilization of recombinant AAV vector reference standards: focus on vector genomes titration by free ITR qPCR

D'Costa, S., Blouin, V., Broucque, F., Penaud-Budloo, M., Fçranois, A., Perez, I. C., Le Bec, C., Moullier, P., Snyder, R. O., & Ayuso, E. (2016) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 89

Human and Insect Cell-Produced Recombinant Adeno-Associated Viruses Show Differences in Genome Heterogeneity

Tran, N. T., Lecomte, E., Saleun, S., Namkung, S., Robin, C., Weber, K., Devine, E., Blouin, V., Adjali, O., Ayuso, E., et al. (2022) · Human Gene Therapy

Virus-based gene therapy researchViral Infectious Diseases and Gene Expression in Insects

Cited by 74

AAV-ID: A Rapid and Robust Assay for Batch-to-Batch Consistency Evaluation of AAV Preparations

Pacouret, S., Bouzelha, M., Shelke, R., Andres-Mateos, E., Xiao, R., Maurer, A., Mevel, M., Turunen, H., Barungi, T., Penaud-Budloo, M., et al. (2017) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 69

Accurate Titration of Infectious AAV Particles Requires Measurement of Biologically Active Vector Genomes and Suitable Controls

François, A., Bouzelha, M., Lecomte, E., Broucque, F., Penaud-Budloo, M., Adjali, O., Moullier, P., Blouin, V., & Ayuso, E. (2018) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 50

The quail mesonephros: a new model for renal senescence?

Nacher, V., Carretero, A., Navarro, M., Armengol, C., Llombart, C., Rodríguez, A., Herrero-Fresneda, I., Ayuso, E., & Ruberte, J. (2006) · Journal of Vascular Research

Telomeres, Telomerase, and SenescenceRenal and related cancers

Cited by 47

Novel chemical tyrosine functionalization of adeno-associated virus improves gene transfer efficiency in liver and retina

Leray, A., Lalys, P.-A., Varin, J., Bouzelha, M., Bourdon, A., Alvarez-Dorta, D., Pavageau, K., Depienne, S., Marchand, M., Mellet, A., et al. (2024) · Biomedicine & Pharmacotherapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 17

Stability of the adeno-associated virus 8 reference standard material

Penaud-Budloo, M., Broucque, F., Harrouet, K., Bouzelha, M., Saleun, S., Douthe, S., D’Costa, S., Ogram, S., Adjali, O., Blouin, V., et al. (2019) · Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 14