O’Shea, John J.

Generation of pathogenic TH17 cells in the absence of TGF-β signalling

Ghoreschi, K., Laurence, A., Yang, X.-P., Tato, C. M., McGeachy, M. J., Konkel, J. E., Ramos, H. L., Wei, L., Davidson, T. S., Bouladoux, N., et al. (2010) · Nature

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

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Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

Milner, J. D., Brenchley, J. M., Laurence, A., Freeman, A. F., Hill, B. J., Elias, K. M., Kanno, Y., Spalding, C., Elloumi, H. Z., Paulson, M. L., et al. (2008) · Nature

Immunodeficiency and Autoimmune DisordersT-cell and B-cell Immunology

Cited by 1,157

Janus kinases in immune cell signaling

Ghoreschi, K., Laurence, A., & O’Shea, J. J. (2009) · Immunological Reviews

Cytokine Signaling Pathways and InteractionsImmunodeficiency and Autoimmune Disorders

Cited by 1,149

Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells

Galon, J., Franchimont, D., Hiroi, N., Frey, G., Boettner, A., Ehrhart-Bornstein, M., O’shea, J. J., Chrousos, G. P., & Bornstein, S. R. (2002) · The FASEB Journal

Estrogen and related hormone effectsAdrenal Hormones and Disorders

Cited by 606

Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection

Yao, C., Sun, H.-W., Lacey, N. E., Ji, Y., Moseman, E. A., Shih, H.-Y., Heuston, E. F., Kirby, M., Anderson, S., Cheng, J., et al. (2019) · Nature Immunology

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 549

Janus kinase-targeting therapies in rheumatology: A mechanisms-based approach

Tanaka, Y., Luo, Y., O’Shea, J. J., & Nakayamada, S. (2022) · Nature Reviews Rheumatology

Cytokine Signaling Pathways and InteractionsRheumatoid Arthritis Research and Therapies

Cited by 501

Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair

Linehan, J. L., Harrison, O. J., Han, S.-J., Byrd, A. L., Vujkovic-Cvijin, I., Villarino, A. V., Sen, S. K., Shaik, J., Smelkinson, M., Tamoutounour, S., et al. (2018) · Cell

T-cell and B-cell ImmunologyDermatology and Skin Diseases

Cited by 456

Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality

Shih, H.-Y., Sciumè, G., Mikami, Y., Guo, L., Sun, H.-W., Brooks, S. R., Urban, J. F., Davis, F. P., Kanno, Y., & O’Shea, J. J. (2016) · Cell

IL-33, ST2, and ILC PathwaysT-cell and B-cell Immunology

Cited by 334

Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis

Deniset, J. F., Belke, D., Lee, W.-Y., Jorch, S. K., Deppermann, C., Hassanabad, A. F., Turnbull, J. D., Teng, G., Rozich, I., Hudspeth, K., et al. (2019) · Immunity

Cardiac Fibrosis and RemodelingCongenital heart defects research

Cited by 178

Interleukin-23-Induced Transcription Factor Blimp-1 Promotes Pathogenicity of T Helper 17 Cells

Jain, R., Chen, Y., Kanno, Y., Joyce-Shaikh, B., Vahedi, G., Hirahara, K., Blumenschein, W. M., Sukumar, S., Haines, C. J., Sadekova, S., et al. (2016) · Immunity

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 167

Human germline heterozygous gain-of-function STAT6 variants cause severe allergic disease

Sharma, M., Leung, D., Momenilandi, M., Jones, L. C. W., Pacillo, L., James, A. E., Murrell, J. R., Delafontaine, S., Maimaris, J., Vaseghi-Shanjani, M., et al. (2023) · Journal of Experimental Medicine

Immunodeficiency and Autoimmune DisordersAsthma and respiratory diseases

Cited by 125

SnapShot: Jak-STAT Signaling II

Villarino, A. V., Gadina, M., O’Shea, J. J., & Kanno, Y. (2020) · Cell

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 85